Kif4a, a member of the kinesin superfamily, has been reported to participate in a series of
cellular processes such as chromosome condensation and cytokinesis during mitosis …

Dehydrobruceine B (DHB) is a quassinoid isolated from Brucea javanica. We have shown
previously that DHB induced apoptosis on two kinds of lung cancer cell lines, A549 and NCI …

The natural environment is replete with potent bioactive organic molecules that are
produced by the microorganisms that inhabit it. These so-called secondary metabolites …

Background Epithelial ovarian cancer (EOC), as a lethal malignancy in women, is often
diagnosed as advanced stages. In contrast, intermediating between benign and malignant …

The cell cycle is a complex sequence of events that directs cell growth and division.
Importantly, the cell cycle regulation is frequently impaired in human cancer cells. The …

This study reports on the spectroscopy-guided isolation and structural elucidation of
secondary metabolites from the New Zealand marine sponge Aaptos confertus. An …

O telômero é uma sequência repetitiva da dupla cadeia do DNA que protege as pontas dos
cromossomos. Seu comprimento é mantido pela telomerase, cuja expressão ocorre em …