Caspases, a family of cysteine proteases is a renowned regulator of apoptosis. Members of
this family are responsible for the proteolytic dismantling of numerous cellular structures …

Glucagon is a prominent peptide hormone, playing central roles in the regulation of glucose
blood-level and lipid metabolism. Formation of glucagon amyloid fibrils has been previously …

Sarcopenia is known as age-related muscle atrophy, which influences over a quarter of the
elderly population worldwide. It is characterized by a progressive decline in muscle mass …

Glucagon stands out as a pivotal peptide hormone, instrumental in controlling blood glucose
levels and lipid metabolism. While the formation of glucagon amyloid fibrils has been …

IPF is a progressive fibrotic lung disease whose pathogenesis remains incompletely
understood. We have previously discovered pathologic mesenchymal progenitor cells …

Long non-coding RNAs (lncRNAs) have been widely implicated in human diseases. Our aim
was to explore the regulatory role of changes in the expression levels of PNKY and its linked …

Many reports have shown that stabilization of secondary structure by stapling functional
peptides enhances the intracellular bioactivity. However, no report has discussed the …

Context BIM (Bcl-2 interacting mediator of apoptosis)-derived peptides that specifically target
over-expressed Mcl-1 (myeloid cell leukemia-1) protein and induce apoptosis are potentially …