To induce bone regeneration there is a complex cascade of growth factors. Growth factors
such as recombinant BMP-2, BMP-7, and PDGF are FDA-approved therapies in bone …

The development, maintenance of healthy bone and regeneration of injured tissue in the
human body comprise a set of intricate and finely coordinated processes. However, an …

Exploring innovative solutions to improve the healthcare of the aging and diseased
population continues to be a global challenge. Among a number of strategies toward this …

Hydrogels are three-dimensional polymeric networks filled with water and mimic tissue
environments. Therefore, they are considered optimal to deliver cells and engineer …

Cell transplantation holds immense potential for reversing diseases that are currently
incurable and for regenerating tissues. However, poor cell survival, cell aggregation and …

Tissue engineering (TE) is a promising approach for repairing diseased and damaged bone
tissue. Injectable hydrogel based strategies offer a wide range of applications in rapid …

Cell therapy has already had an important impact on healthcare and provided new
treatments for previously intractable diseases. Notable examples include mesenchymal …

This is the first report, to our knowledge, of the preparation of an injectable in situ–forming
click-crosslinked hyaluronic acid (Cx-HA) hydrogel (Cx-HA-CM) containing chemical …

Dental problems including cavities, periodontitis, apical periodontitis, and pulpitis are among
the most cost-consuming burden for both patients and the health care system all over the …

Current surgical treatments and material applications are not ideal for the treatment of
orthopedic clinical injuries, such as large bone defects, cartilage defects, and vascular …