[HTML][HTML] Articular cartilage and osteochondral tissue engineering techniques: Recent advances and challenges

W Wei, H Dai - Bioactive materials, 2021 - Elsevier
In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

[HTML][HTML] An overview of substrate stiffness guided cellular response and its applications in tissue regeneration

B Yi, Q Xu, W Liu - Bioactive materials, 2022 - Elsevier
Cell-matrix interactions play a critical role in tissue repair and regeneration. With gradual
uncovering of substrate mechanical characteristics that can affect cell-matrix interactions …

Surgical and tissue engineering strategies for articular cartilage and meniscus repair

H Kwon, WE Brown, CA Lee, D Wang… - Nature Reviews …, 2019 - nature.com
Injuries to articular cartilage and menisci can lead to cartilage degeneration that ultimately
results in arthritis. Different forms of arthritis affect~ 50 million people in the USA alone, and it …

Digital light processing based bioprinting with composable gradients

M Wang, W Li, LS Mille, T Ching, Z Luo… - Advanced …, 2022 - Wiley Online Library
Recapitulation of complex tissues signifies a remarkable challenge and, to date, only a few
approaches have emerged that can efficiently reconstruct necessary gradients in 3D …

[HTML][HTML] Hyaluronic acid and chondroitin sulfate (meth) acrylate-based hydrogels for tissue engineering: Synthesis, characteristics and pre-clinical evaluation

CCL Schuurmans, M Mihajlovic, C Hiemstra, K Ito… - Biomaterials, 2021 - Elsevier
Hydrogels based on photocrosslinkable Hyaluronic Acid Methacrylate (HAMA) and
Chondroitin Sulfate Methacrylate (CSMA) are presently under investigation for tissue …

[HTML][HTML] Integrated gradient tissue-engineered osteochondral scaffolds: Challenges, current efforts and future perspectives

X Niu, N Li, Z Du, X Li - Bioactive Materials, 2023 - Elsevier
The osteochondral defect repair has been most extensively studied due to the rising
demand for new therapies to diseases such as osteoarthritis. Tissue engineering has been …

3D bioprinting dual-factor releasing and gradient-structured constructs ready to implant for anisotropic cartilage regeneration

Y Sun, Y You, W Jiang, B Wang, Q Wu, K Dai - Science advances, 2020 - science.org
Cartilage injury is extremely common and leads to joint dysfunction. Existing joint prostheses
do not remodel with host joint tissue. However, developing large-scale biomimetic …

Advances in the fabrication of biomaterials for gradient tissue engineering

C Li, L Ouyang, JPK Armstrong, MM Stevens - Trends in biotechnology, 2021 - cell.com
Natural tissues and organs exhibit an array of spatial gradients, from the polarized neural
tube during embryonic development to the osteochondral interface present at articulating …

Extrusion and microfluidic‐based bioprinting to fabricate biomimetic tissues and organs

E Davoodi, E Sarikhani, H Montazerian… - Advanced materials …, 2020 - Wiley Online Library
Next generation engineered tissue constructs with complex and ordered architectures aim to
better mimic the native tissue structures, largely due to advances in 3D bioprinting …

Biofabrication of spatially organised tissues by directing the growth of cellular spheroids within 3D printed polymeric microchambers

AC Daly, DJ Kelly - Biomaterials, 2019 - Elsevier
Successful tissue engineering requires the generation of human scale implants that mimic
the structure, composition and mechanical properties of native tissues. Here, we report a …