[HTML][HTML] Molecular alterations in cutaneous squamous cell carcinoma in immunocompetent and immunosuppressed hosts—A systematic review
DA Tsang, SYC Tam, CC Oh - Cancers, 2023 - mdpi.com
Simple Summary Cutaneous squamous cell carcinoma (cSCC) is the second most common
form of skin cancer worldwide. Due to its high mutational burden, cSCC remains poorly …
form of skin cancer worldwide. Due to its high mutational burden, cSCC remains poorly …
[HTML][HTML] Chondroitin sulfate proteoglycan 4 as a marker for aggressive squamous cell carcinoma
Simple Summary Many solid tumours, such as those of the breast, colon, and prostate, have
well established molecular markers of malignancy. However, in certain cancers, such as …
well established molecular markers of malignancy. However, in certain cancers, such as …
[HTML][HTML] Sex as a predictor of response to immunotherapy in advanced cutaneous squamous cell carcinoma
Simple Summary Cutaneous squamous cell carcinomas (CSCC) are the second most
common skin cancer amongst Caucasians, accounting for up to 20–25% of skin cancers …
common skin cancer amongst Caucasians, accounting for up to 20–25% of skin cancers …
[HTML][HTML] Whole genome analysis reveals the genomic complexity in metastatic cutaneous squamous cell carcinoma
Metastatic cutaneous squamous cell carcinoma (CSCC) is a highly morbid disease requiring
radical surgery and adjuvant therapy, which is associated with a poor prognosis. Yet …
radical surgery and adjuvant therapy, which is associated with a poor prognosis. Yet …
[HTML][HTML] PIK your poison: the effects of combining PI3K and CDK inhibitors against metastatic cutaneous squamous cell carcinoma in vitro
Simple Summary Cutaneous squamous cell carcinoma (cSCC) is a very common skin
cancer with poor prognosis for patients with advanced disease. PI3K/AKT/mTOR and cell …
cancer with poor prognosis for patients with advanced disease. PI3K/AKT/mTOR and cell …
[HTML][HTML] Adipose tissue-derived extracellular vesicles contribute to phenotypic plasticity of prostate cancer cells
A Mathiesen, B Haynes, R Huyck, M Brown… - International Journal of …, 2023 - mdpi.com
Metastatic prostate cancer is one of the leading causes of male cancer deaths in the western
world. Obesity significantly increases the risk of metastatic disease and is associated with a …
world. Obesity significantly increases the risk of metastatic disease and is associated with a …
[HTML][HTML] A tEMTing target? Clinical and experimental evidence for epithelial-mesenchymal transition in the progression of cutaneous squamous cell carcinoma (a …
Cutaneous squamous cell carcinoma (cSCC) is a disease with globally rising incidence and
poor prognosis for patients with advanced or metastatic disease. Epithelial-mesenchymal …
poor prognosis for patients with advanced or metastatic disease. Epithelial-mesenchymal …
[HTML][HTML] Targeted imaging of uPAR expression in vivo with cyclic AE105 variants
JM Leth, EA Newcombe, AL Grønnemose… - Scientific Reports, 2023 - nature.com
A comprehensive literature reports on the correlation between elevated levels of urokinase-
type plasminogen activator receptor (uPAR) and the severity of diseases with chronic …
type plasminogen activator receptor (uPAR) and the severity of diseases with chronic …
Recent advances in targeting the urokinase plasminogen activator with nanotherapeutics
The aberrant proteolytic landscape of the tumor microenvironment is a key contributor of
cancer progression. Overexpression of urokinase plasminogen activator (uPA) and/or its …
cancer progression. Overexpression of urokinase plasminogen activator (uPA) and/or its …
Genomic progression for local invasion of cutaneous squamous cell carcinoma from the superficial to the deep portion
Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer.
While many treatments exist, our understanding of its genomic progression, especially from …
While many treatments exist, our understanding of its genomic progression, especially from …