Recent advances in designing 5-fluorouracil delivery systems: a stepping stone in the safe treatment of colorectal cancer

E Entezar-Almahdi, S Mohammadi-Samani… - International journal …, 2020 - Taylor & Francis
Fluorouracil (5-FU) has become one of the most widely employed antimetabolite
chemotherapeutic agents in recent decades. It is considered a first line antineoplastic agent …

Chitosan/carbon quantum dot/aptamer complex as a potential anticancer drug delivery system towards the release of 5-fluorouracil

HS Zavareh, M Pourmadadi, A Moradi… - International Journal of …, 2020 - Elsevier
Nowadays, nanotechnology contributes diminishing side effects rather than traditional
therapeutic methods like chemotherapy. Thus, designing a biocompatible specific targeted …

Current advances in drug delivery of nanoparticles for respiratory disease treatment

BRC de Menezes, KF Rodrigues… - Journal of Materials …, 2021 - pubs.rsc.org
Cases of respiratory diseases have been increasing around the world, affecting the health
and quality of life of millions of people every year. Chronic respiratory diseases (CRDs) and …

A calcium phosphate drug carrier loading with 5-fluorouracil achieving a synergistic effect for pancreatic cancer therapy

J Chen, M Qiu, S Zhang, B Li, D Li, X Huang… - Journal of Colloid and …, 2022 - Elsevier
Calcium based biomaterials were widely used for drug delivery application due to their
biodegradability, biocompatibility, and high drug loading capacity. Herein, amino-capped …

A solvatochromic AIE tetrahydro [5] helicene derivative as fluorescent probes for water in organic solvents and highly sensitive sensors for glyceryl monostearate

L Cai, X Sun, W He, R Hu, B Liu, J Shen - Talanta, 2020 - Elsevier
In this paper, a tetrahydro [5] helicene-based imide dye with thienyl group (THID) was
studied on its solvatochromism and aggregation-induced emission (AIE) properties by …

[PDF][PDF] Preparation and characterization of folated chitosan-magnetic nanocarrier for 5-fluorouracil drug delivery and studying its effect in bladder cancer therapy

S Al-Musawi, AJ Hadi, SJ Hadi… - J. Glob. Pharm. Technol, 2019 - researchgate.net
Among the vigorous anticancer factors, 5-Fluorouracil (5-FU) has been presented fantastic
capability against several types of tumor cells. Chitosan-covered super paramagnetic iron …

Development of amine-functionalized porous organosilica nanoparticles as pH-responsive drug delivery system

NXD Mai, HVT Nguyen, TM Phung, TM Le… - Journal of Drug Delivery …, 2023 - Elsevier
This study presents the synthesis and characterization of amine-functionalized
biodegradable periodic mesoporous organosilica (BPMO-NH 2) as a promising drug …

Targeted Anticancer Drug Delivery Using Chitosan, Carbon Quantum Dots, and Aptamers to Deliver Ganoderic Acid and 5‐Fluorouracil

A Mazandarani, A Taravati… - Chemistry & …, 2023 - Wiley Online Library
Breast cancer is a malignancy that affects mostly females and is among the most lethal types
of cancer. The ligand‐functionalized nanoparticles used in the nano‐drug delivery system …

Deciphering the mechanism of action involved in enhanced suicide gene colon cancer cell killer effect mediated by gef and apoptin

B Cáceres, A Ramirez, E Carrillo, G Jimenez… - Cancers, 2019 - mdpi.com
Despite the great advances in cancer treatment, colorectal cancer has emerged as the
second highest cause of death from cancer worldwide. For this type of tumor, the use of …

Fabrication and characterization of starch/agarose biopolymers containing graphene oxide towards the release of 5-fluorouracil in cancer treatment

M Ghotbi, M Pourmadadi, F Yazdian… - Inorganic Chemistry …, 2024 - Elsevier
The use of drug nanocarriers with effective drug loading can be effective in cancer treatment.
In this study, graphene oxide (GO)/agarose (Aga)/starch (S) nanocarriers were made to …