Obesity is a major determinant of health outcomes and is on the increase in women world-
wide. It predisposes to surgical site infection (SSI). Risk factors for the SSI include extremes …

Obesity is a worldwide health problem; its prevalence is increasing in all age groups,
including those of childbearing age. Currently in the UK, 23.1% of the antenatal population …

Currently, there is no consensus on whether a standard 2-g prophylactic cefazolin dose
provides sufficient antimicrobial coverage in obese surgical patients. This systematic review …

(1) Background: Caesarean sections in obese patients are associated with an increased risk
of surgical wound complications, including hematomas, seromas, abscesses, dehiscence …

The perinatal period sets the basis for the later physiological and immune homeostasis of
the individual, with the intestinal microbiota being an important contributor to driving this …

The objective of this study was to evaluate the steady state pharmacokinetics and
pharmacodynamics of cefazolin in patients with a high body weight. Cefazolin was …

Appropriate surgical antimicrobial prophylaxis (SAP) is an important measure in preventing
surgical site infections (SSIs). Although antimicrobial pharmacokinetics–pharmacodynamics …

Objectives To assess plasma and tissue pharmacokinetics of cefazolin and metronidazole in
obese patients undergoing bariatric surgery and non-obese patients undergoing intra …

Intravenous (IV) cefuroxime and cefazolin are used prophylactically in caesarean sections
(CS). Currently, there are concerns regarding sub-optimal dosing in obese pregnant women …

The aim of this study was to analyze the population pharmacokinetics of total and unbound
concentrations of prophylactic cefazolin (CFZ) in patients with prostatectomy or …