Equilibrium mechanisms of self-limiting assembly

MF Hagan, GM Grason - Reviews of modern physics, 2021 - APS
Self-assembly is a ubiquitous process in synthetic and biological systems, broadly defined
as the spontaneous organization of multiple subunits (macromolecules, particles, etc.) into …

Theoretical aspects of virus capsid assembly

A Zlotnick - Journal of Molecular Recognition: An …, 2005 - Wiley Online Library
A virus capsid is constructed from many copies of the same protein (s). Molecular
recognition is central to capsid assembly. The capsid protein must polymerize in order to …

A multiscale model of virus pandemic: Heterogeneous interactive entities in a globally connected world

N Bellomo, R Bingham, MAJ Chaplain… - … Models and Methods …, 2020 - World Scientific
This paper is devoted to the multidisciplinary modelling of a pandemic initiated by an
aggressive virus, specifically the so-called SARS–CoV–2 Severe Acute Respiratory …

Origin of icosahedral symmetry in viruses

R Zandi, D Reguera, RF Bruinsma… - Proceedings of the …, 2004 - National Acad Sciences
With few exceptions, the shells (capsids) of sphere-like viruses have the symmetry of an
icosahedron and are composed of coat proteins (subunits) assembled in special motifs, the …

[HTML][HTML] Dynamic pathways for viral capsid assembly

MF Hagan, D Chandler - Biophysical journal, 2006 - cell.com
We develop a class of models with which we simulate the assembly of particles into T1
capsidlike objects using Newtonian dynamics. By simulating assembly for many different …

Modeling viral capsid assembly

MF Hagan - Advances in Chemical Physics: Volume 155, 2014 - Wiley Online Library
Viruses play a role in a significant portion of human diseases, as well as those of other
animals, plants, and bacteria. This chapter focuses on the use of theoretical and …

Structural puzzles in virology solved with an overarching icosahedral design principle

R Twarock, A Luque - Nature communications, 2019 - nature.com
Viruses have evolved protein containers with a wide spectrum of icosahedral architectures
to protect their genetic material. The geometric constraints defining these container designs …

Deciphering the kinetic mechanism of spontaneous self-assembly of icosahedral capsids

HD Nguyen, VS Reddy, CL Brooks - Nano letters, 2007 - ACS Publications
Self-assembly of viral proteins into icosahedral capsids is an interesting yet poorly
understood phenomenon of which elucidation may aid the exploration of beneficial …

Trapping of hepatitis B virus capsid assembly intermediates by phenylpropenamide assembly accelerators

SP Katen, SR Chirapu, MG Finn… - ACS chemical biology, 2010 - ACS Publications
Understanding the biological self-assembly process of virus capsids is key to understanding
the viral life cycle, as well as serving as a platform for the design of assembly-based antiviral …

Role of reversibility in viral capsid growth: a paradigm for self-assembly

DC Rapaport - Physical Review Letters, 2008 - APS
Self-assembly at submicroscopic scales is an important but little understood phenomenon. A
prominent example is virus capsid growth, whose underlying behavior can be modeled …