Nanoscale materials are increasingly found in consumer goods, electronics, and
pharmaceuticals. While these particles interact with the body in myriad ways, their beneficial …

Cancer is the second worldwide cause of death, exceeded only by cardiovascular diseases.
It is characterized by uncontrolled cell proliferation and an absence of cell death that, except …

Engineered nanoparticles have the potential to revolutionize the diagnosis and treatment of
many diseases; for example, by allowing the targeted delivery of a drug to particular subsets …

Nanomedicines and macromolecular drugs can induce hypersensitivity reactions (HSRs)
with symptoms ranging from flushing and breathing difficulties to hypothermia, hypotension …

Depending on the context, nanotechnologies developed as nanomedicines (nanosized
therapeutics and imaging agents) are presented as either a remarkable technological …

Nanocarriers offer unique possibilities to overcome cellular barriers in order to improve the
delivery of various drugs and drug candidates, including the promising therapeutic …

Numerous investigations have shown that both tissue and cell distribution profiles of
anticancer drugs can be controlled by their entrapment in submicronic colloidal systems …

The transfer of polymer–protein conjugates into routine clinical use, and the clinical
development of polymer–anticancer-drug conjugates, both as single agents and as …

Nanotechnology can be defined as the science and engineering involved in the design,
synthesis, characterization and application of materials and devices whose smallest …

The blood–brain barrier (BBB) represents an insurmountable obstacle for a large number of
drugs, including antibiotics, antineoplastic agents, and a variety of central nervous system …