Objectives: An overview of biochemical markers of bone metabolism is presented along with
indications for their clinical utilization. Design and Methods: The structure, cyclical …

I. Introduction A LTHOUGH osteoporosis has long been considered a disease of women, in
the earliest reports of the epidemiology of osteoporosis it was apparent that the classical age …

Abstract Changes of bone turnover with aging are responsible for bone loss and play a
major role in osteoporosis. Although an increase of bone turnover has been documented at …

Collagen is the main source of extracellular support for multicellular animals. The
mechanical strength of collagen fibrils depends on a highly regulated mechanism of …

Inhaled corticosteroids are considered by many to be the anti-inflammatory therapy of choice
in adult asthma, given their remarkable efficacy and apparent safety. They are presently …

Protracted critical illness is marked by protein wasting resistant to feeding, by accumulation
of fat stores, and by suppressed pulsatile release of GH and TSH. We previously showed …

Circulating biochemical markers of bone remodeling in uremic patients. Chronic renal failure
is often associated with bone disorders, including secondary hyperparathyroidism …

Several studies in recent years have shown that the pyridinium crosslinks of collagen
provide good urinary markers of collagen degradation, primarily reflecting bone resorption …

The noninvasive assessment of bone turnover has received increasing attention over the
past few years because of the need for sensitive markers in the clinical investigation of …

Indirect indices of exercise-induced human skeletal muscle damage and connective tissue
breakdown were studied following a single bout of voluntary eccentric muscle contractions …