[HTML][HTML] Quantitative approaches in multimodal fundus imaging: state of the art and future perspectives

A Arrigo, E Aragona, MB Parodi, F Bandello - Progress in Retinal and Eye …, 2023 - Elsevier
When it first appeared, multimodal fundus imaging revolutionized the diagnostic workup and
provided extremely useful new insights into the pathogenesis of fundus diseases. The recent …

AI in the clinical management of GA: a novel therapeutic universe requires novel tools

GS Reiter, J Mai, S Riedl, K Birner, S Frank… - Progress in Retinal and …, 2024 - Elsevier
Regulatory approval of the first two therapeutic substances for the management of
geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is a major …

Clinically relevant deep learning for detection and quantification of geographic atrophy from optical coherence tomography: a model development and external …

G Zhang, DJ Fu, B Liefers, L Faes, S Glinton… - The Lancet Digital …, 2021 - thelancet.com
Background Geographic atrophy is a major vision-threatening manifestation of age-related
macular degeneration, one of the leading causes of blindness globally. Geographic atrophy …

Oral antioxidant and lutein/zeaxanthin supplements slow geographic atrophy progression to the fovea in age-related macular degeneration

TDL Keenan, E Agrón, PA Keane, A Domalpally… - Ophthalmology, 2025 - Elsevier
Purpose To determine whether oral micronutrient supplementation slows geographic
atrophy (GA) progression in age-related macular degeneration (AMD). Design Post hoc …

[HTML][HTML] Disease activity and therapeutic response to pegcetacoplan for geographic atrophy identified by deep learning-based analysis of OCT

U Schmidt-Erfurth, J Mai, GS Reiter, S Riedl, WD Vogl… - Ophthalmology, 2024 - Elsevier
Purpose To quantify morphological changes of the photoreceptors (PRs) and retinal pigment
epithelium (RPE) layers under pegcetacoplan therapy in geographic atrophy (GA) using …

Clinical validation for automated geographic atrophy monitoring on OCT under complement inhibitory treatment

J Mai, D Lachinov, S Riedl, GS Reiter, WD Vogl… - Scientific Reports, 2023 - nature.com
Geographic atrophy (GA) represents a late stage of age-related macular degeneration,
which leads to irreversible vision loss. With the first successful therapeutic approach, namely …

Artificial intelligence in retinal image analysis: Development, advances, and challenges

AC Oganov, I Seddon, S Jabbehdari, OE Uner… - Survey of …, 2023 - Elsevier
Modern advances in diagnostic technologies offer the potential for unprecedented insight
into ophthalmic conditions relating to the retina. We discuss the current landscape of artificial …

Pegcetacoplan treatment and consensus features of geographic atrophy over 24 months

DJ Fu, P Bagga, G Naik, S Glinton, L Faes… - JAMA …, 2024 - jamanetwork.com
Importance Despite widespread availability and consensus on its advantages for detailed
imaging of geographic atrophy (GA), spectral-domain optical coherence tomography (SD …

[HTML][HTML] Geographic atrophy segmentation using multimodal deep learning

T Spaide, J Jiang, J Patil, N Anegondi… - … Vision Science & …, 2023 - iovs.arvojournals.org
Purpose: To examine deep learning (DL)–based methods for accurate segmentation of
geographic atrophy (GA) lesions using fundus autofluorescence (FAF) and near-infrared …

Risk classification for progression to subfoveal geographic atrophy in dry age-related macular degeneration using machine learning–enabled outer retinal feature …

K Sarici, JR Abraham, DD Sevgi… - … Surgery, Lasers and …, 2022 - journals.healio.com
BACKGROUND AND OBJECTIVE: To evaluate the utility of spectral-domain optical
coherence tomography biomarkers to predict the development of subfoveal geographic …