No matter what their origin, strain and family, viruses have evolved exquisite strategies to
reach and penetrate specific target cells where they hijack the cellular machinery to express …

The mature lymphocyte population of a healthy individual has the remarkable ability to
recognise an immense variety of antigens. Instead of encoding a unique gene for each …

With combined antiretroviral therapy (cART), the risk for HIV-infected individuals to develop
a non-Hodgkin lymphoma is diminished. However, the incidence of Burkitt lymphoma (BL) …

Retinitis pigmentosa (RP) is a group of inherited retinal disorders characterized by
progressive loss of photoreceptors and eventually leads to retina degeneration and atrophy …

Ku, a cellular complex required for human cell survival and involved in double strand break
DNA repair and multiple other cellular processes, may modulate retroviral multiplication …

During evolution, viruses had to adapt to an increasingly complex environment of eukaryotic
cells. Viral proteins that need to enter the cell nucleus or associate with nucleoli possess …

Integration of HIV-1 linear DNA into host chromatin is required for high levels of viral
expression, and constitutes a key therapeutic target. Unintegrated viral DNA (uDNA) can …

Laminins are essential components of all basement membranes where they regulate an
extensive array of tissue functions. Alternative splicing from the laminin α3 gene produces a …

Abstract Xenotropic Murine leukemia virus-Related Virus (XMRV) directly arose from genetic
recombinations between two endogenous murine retroviruses that occurred during human …

Une meilleure connaissance des déterminants viraux et cellulaires impliqués dans la
régulation de l'expression lentivirale est essentielle pour (i) maitriser l'expression d'un …