Microorganisms within the gut and other niches may contribute to carcinogenesis, as well as
shaping cancer immunosurveillance and response to immunotherapy. Our understanding of …

Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

Microbiome studies have become routine in biomedical, agricultural and environmental
sciences with diverse aims, including diversity profiling, functional characterization, and …

Microbiotas are a malleable part of ecosystems, including the human ecosystem.
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …

Plant secondary metabolites (PSMs) play many roles including defense against pathogens,
pests, and herbivores; response to environmental stresses, and mediating organismal …

Abstract The NIH Human Microbiome Project (HMP) has been carried out over ten years and
two phases to provide resources, methods, and discoveries that link interactions between …

Global environmental contamination with a complex mixture of xenobiotics has become a
major environmental issue worldwide. Many xenobiotic compounds severely impact the …

The gut microbiota produce hundreds of small molecules, many of which modulate host
physiology. Although efforts have been made to identify biosynthetic genes for secondary …

Asthma is a multifactorial disorder, and microbial dysbiosis enhances lung inflammation and
asthma-related symptoms. Probiotics have shown anti-inflammatory effects and could …

The interactions between the gut microbiome and metabolome play an important role in
human health and diseases. Current studies mainly apply statistical correlation analysis …