[HTML][HTML] Alzheimer's disease as a viral disease: Revisiting the infectious hypothesis
Alzheimer's disease (AD) represents the most frequent type of dementia in elderly people.
Two major forms of the disease exist: sporadic-the causes of which have not yet been fully …
Two major forms of the disease exist: sporadic-the causes of which have not yet been fully …
Molecular recognition in chemical and biological systems
E Persch, O Dumele, F Diederich - … Chemie International Edition, 2015 - Wiley Online Library
Abstract Structure‐based ligand design in medicinal chemistry and crop protection relies on
the identification and quantification of weak noncovalent interactions and understanding the …
the identification and quantification of weak noncovalent interactions and understanding the …
HIV infection
More than 75 million people worldwide have been infected with human immunodeficiency
virus (HIV), and there are now approximately 37 million individuals living with the infection …
virus (HIV), and there are now approximately 37 million individuals living with the infection …
Cardiovascular disease and thrombosis in HIV infection
MV Perkins, SB Joseph, DP Dittmer… - … , and vascular biology, 2023 - Am Heart Assoc
HIV infection has transitioned from an acute, fatal disease to a chronic one managed by
antiretroviral therapy. Thus, the aging population of people living with HIV (PLWH) continues …
antiretroviral therapy. Thus, the aging population of people living with HIV (PLWH) continues …
Antivirals with common targets against highly pathogenic viruses
Historically, emerging viruses appear constantly and have cost millions of human lives.
Currently, climate change and intense globalization have created favorable conditions for …
Currently, climate change and intense globalization have created favorable conditions for …
[HTML][HTML] The paradox of HIV blood–brain barrier penetrance and antiretroviral drug delivery deficiencies
HIV attacks the body's immune cells, frequently compromises the integrity of the blood–brain
barrier (BBB), and infects the CNS in the early stages of infection. Dysfunction of the BBB …
barrier (BBB), and infects the CNS in the early stages of infection. Dysfunction of the BBB …
Potential resistance of SARS-CoV-2 main protease (Mpro) against protease inhibitors: lessons learned from HIV-1 protease
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome 2
(SARS-CoV-2), has been one of the most devastating pandemics of recent times. The lack of …
(SARS-CoV-2), has been one of the most devastating pandemics of recent times. The lack of …
APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages
S Sharma, SK Patnaik, R Thomas Taggart… - Nature …, 2015 - nature.com
The extent, regulation and enzymatic basis of RNA editing by cytidine deamination are
incompletely understood. Here we show that transcripts of hundreds of genes undergo site …
incompletely understood. Here we show that transcripts of hundreds of genes undergo site …
Silver nanoparticles as potential antiviral agents
Since the early 1990s, nanotechnology has led to new horizons in nanomedicine, which
encompasses all spheres of science including chemistry, material science, biology, and …
encompasses all spheres of science including chemistry, material science, biology, and …
HIV Gag polyprotein: processing and early viral particle assembly
NM Bell, AML Lever - Trends in microbiology, 2013 - cell.com
Over the past several decades, extensive research into the Gag polyprotein, the main
structural protein of HIV-1 and all other retroviruses, has changed the way that we describe …
structural protein of HIV-1 and all other retroviruses, has changed the way that we describe …