Human brain connectivity: Clinical applications for clinical neurophysiology

M Hallett, W de Haan, G Deco, R Dengler… - Clinical …, 2020 - Elsevier
This manuscript is the second part of a two-part description of the current status of
understanding of the network function of the brain in health and disease. We start with the …

A review on pathology, mechanism, and therapy for cerebellum and tremor in Parkinson's disease

Y Zhong, H Liu, G Liu, L Zhao, C Dai, Y Liang… - npj Parkinson's …, 2022 - nature.com
Tremor is one of the core symptoms of Parkinson's disease (PD), but its mechanism is poorly
understood. The cerebellum is a growing focus in PD-related researches and is reported to …

[HTML][HTML] The effect of network thresholding and weighting on structural brain networks in the UK Biobank

CR Buchanan, ME Bastin, SJ Ritchie, DC Liewald… - NeuroImage, 2020 - Elsevier
Whole-brain structural networks can be constructed using diffusion MRI and probabilistic
tractography. However, measurement noise and the probabilistic nature of the tracking …

Relative sparing of dopaminergic terminals in the caudate nucleus is a feature of rest tremor in Parkinson's disease

MD Mendonça, PC Ferreira, F Oliveira… - npj Parkinson's …, 2024 - nature.com
Resting tremor (RT) is a Parkinson's disease (PD) symptom with an unclear relationship to
the dopaminergic system. We analysed data from 432 subjects from the Parkinson's …

Cerebro-cerebellar motor networks in clinical subtypes of Parkinson's disease

S Basaia, F Agosta, A Francia, C Cividini… - npj Parkinson's …, 2022 - nature.com
Parkinson's disease (PD) patients can be classified in tremor-dominant (TD) and postural-
instability-and-gait-disorder (PIGD) motor subtypes. PIGD represents a more aggressive …

The Basal Ganglia: More than just a switching device

TM Florio, E Scarnati, I Rosa… - CNS neuroscience & …, 2018 - Wiley Online Library
The basal ganglia consist of a variety of subcortical nuclei engaged in motor control and
executive functions, such as motor learning, behavioral control, and emotion. The striatum, a …

Neuroimaging detectable differences between Parkinson's disease motor subtypes: a systematic review

JT Boonstra, S Michielse, Y Temel… - Movement disorders …, 2021 - Wiley Online Library
Background The neuroanatomical substrates of Parkinson's disease (PD) with tremor‐
dominance (TD) and those with non‐tremor dominance (nTD), postural instability and gait …

Free-water imaging in white and gray matter in Parkinson's disease

C Andica, K Kamagata, T Hatano, A Saito, W Uchida… - Cells, 2019 - mdpi.com
This study aimed to discriminate between neuroinflammation and neuronal degeneration in
the white matter (WM) and gray matter (GM) of patients with Parkinson's disease (PD) using …

PET imaging of synaptic density in Parkinsonian disorders

SL Martin, C Uribe, AP Strafella - Journal of Neuroscience …, 2024 - Wiley Online Library
Synaptic dysfunction and altered synaptic pruning are present in people with Parkinsonian
disorders. Dopamine loss and alpha‐synuclein accumulation, two hallmarks of Parkinson's …

Neurobiology of placebo effect in Parkinson's disease: What we have learned and where we are going

A Quattrone, G Barbagallo, A Cerasa… - Movement …, 2018 - Wiley Online Library
The placebo effect is a phenomenon produced when an inert substance administered like a
regular treatment improves the clinical outcome. Parkinson's disease (PD) is one of the main …