Flow fine synthesis with heterogeneous catalysts
In the past few decades, organic reactions under flow conditions have attracted increasing
attention. Flow reactions have a number of advantages over batch reactions in terms of …
attention. Flow reactions have a number of advantages over batch reactions in terms of …
The expanding utility of continuous flow hydrogenation
There has been an increasing body of evidence that flow hydrogenation enhances reduction
outcomes across a wide range of synthetic transformations. Moreover flow reactors enhance …
outcomes across a wide range of synthetic transformations. Moreover flow reactors enhance …
Flow synthesis approaches to privileged scaffolds–recent routes reviewed for green and sustainable aspects
AI Alfano, M Brindisi, H Lange - Green Chemistry, 2021 - pubs.rsc.org
Privileged scaffolds as starting points toward biologically active molecules represent a
neuralgic point in drug discovery. The ability of synthetic chemists concerned with their …
neuralgic point in drug discovery. The ability of synthetic chemists concerned with their …
[HTML][HTML] Palladium-catalyzed Suzuki–Miyaura cross-coupling in continuous flow
Carbon–carbon cross-coupling reactions are among the most important processes in
organic chemistry and Suzuki–Miyaura reactions are the most widely used protocols. For a …
organic chemistry and Suzuki–Miyaura reactions are the most widely used protocols. For a …
Benchmarking immobilized di-and triarylphosphine palladium catalysts for continuous-flow cross-coupling reactions: efficiency, durability, and metal leaching studies
Leaching resistance and recyclability, in addition to efficiency, are key parameters which
constrain the choice of a catalyst for performing metal-catalyzed cross-coupling reactions in …
constrain the choice of a catalyst for performing metal-catalyzed cross-coupling reactions in …
A highly responsive, sensitive NIR fluorescent probe for imaging of superoxide anion in mitochondria of oral cancer cells
S Jiao, J Zhai, S Yang, X Meng - Talanta, 2021 - Elsevier
Abstract Superoxide anion (O 2•-) is an important biomarker for reactive oxygen species
(ROS) generated through physiological and pathological processes. However, due to the …
(ROS) generated through physiological and pathological processes. However, due to the …
[HTML][HTML] Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation
A Sidarovich, CL Will, MM Anokhina, J Ceballos… - Elife, 2017 - elifesciences.org
Small molecule inhibitors of pre-mRNA splicing are important tools for identifying new
spliceosome assembly intermediates, allowing a finer dissection of spliceosome dynamics …
spliceosome assembly intermediates, allowing a finer dissection of spliceosome dynamics …
A NIR emitting cyanine with large stokes' shift for mitochondria and identification of their membrane potential disruption
An NIR emitting (λem≈ 730 nm) cyanine probe ExCy was synthesized in good yields by
extending the π‐conjugation length (ie, with furan moiety) to the donor‐accepter system …
extending the π‐conjugation length (ie, with furan moiety) to the donor‐accepter system …
Catalytic Advancements: Optimizing Pd-Based Cross-Coupling Reactions Through Flow Chemistry
Flow chemistry is a method of conducting a reaction in continuous flow through channels by
pumping the reactants into the system. This advanced method offers rapid and efficient …
pumping the reactants into the system. This advanced method offers rapid and efficient …
[HTML][HTML] Development of facile and simple processes for the heterogeneous Pd-catalyzed ligand-free continuous-flow Suzuki–Miyaura coupling
The Suzuki–Miyaura coupling reaction is one of the most widely utilized C–C bond forming
methods to create (hetero) biaryl scaffolds. The continuous-flow reaction using …
methods to create (hetero) biaryl scaffolds. The continuous-flow reaction using …