Absorption, metabolism, and bioactivity of vitexin: recent advances in understanding the efficacy of an important nutraceutical

Y Peng, R Gan, H Li, M Yang… - Critical Reviews in …, 2021 - Taylor & Francis
Abstract vitexin, an apigenin-8-C-glucoside, is widely present in numerous edible and
medicinal plants. vitexin possesses a variety of bioactive properties, including antioxidation …

Multitargeted effects of vitexin and isovitexin on diabetes mellitus and its complications

IL Abdulai, SK Kwofie, WS Gbewonyo… - The Scientific World …, 2021 - Wiley Online Library
Background. Till date, there is no known antidote to cure diabetes mellitus despite the
discovery and development of diverse pharmacotherapeutic agents many years ago …

The use of natural compounds as a strategy to counteract oxidative stress in animal models of diabetes mellitus

M Salazar-García, JC Corona - International Journal of Molecular …, 2021 - mdpi.com
Diabetes mellitus (DM) is a chronic metabolic disease characterised by insulin deficiency,
resulting in hyperglycaemia, a characteristic symptom of type 2 diabetes mellitus (DM2). DM …

[HTML][HTML] A systematic review of preclinical studies exploring the role of insulin signalling in executive function and memory

AM Ottomana, M Presta, A O'Leary, M Sullivan… - … & biobehavioral reviews, 2023 - Elsevier
Beside its involvement in somatic dysfunctions, altered insulin signalling constitutes a risk
factor for the development of mental disorders like Alzheimer's disease and obsessive …

The Effects of Hydrogen Peroxide on Plant Growth, Mineral Accumulation, as Well as Biological and Chemical Properties of Ficus deltoidea

N Nurnaeimah, N Mat, K Suryati Mohd, NA Badaluddin… - Agronomy, 2020 - mdpi.com
Hydrogen peroxide (H2O2) is defined as a reactive oxygen species (ROS), able to cause
damage to a variety of cellular structures. On the other hand, recent work has demonstrated …

[HTML][HTML] The protective effect of formononetin on cognitive impairment in streptozotocin (STZ)-induced diabetic mice

J Wang, L Wang, J Zhou, A Qin, Z Chen - Biomedicine & Pharmacotherapy, 2018 - Elsevier
The present study was aimed to elucidate the pharmacological effect of Formononetin (FMN)
treatment on STZ-induced diabetic cognitive dysfunction. The diabetic model was induced …

Beneficial role of Vitexin in Parkinson's disease

M Mustapha, CNM Taib - The Malaysian journal of medical …, 2022 - pmc.ncbi.nlm.nih.gov
Today, Parkinson's disease (PD) is the foremost neurological disorder all across the globe.
In the quest for a novel therapeutic agent for PD with a multimodal mechanism of action and …

[HTML][HTML] Therapeutic effects of aqueous extract of bioactive active component of Ageratum conyzoides on the ovarian-uterine and hypophysis-gonadal axis in rat with …

SA Adelakun, VO Ukwenya, AB Peter, AJ Siyanbade… - Metabolism Open, 2022 - Elsevier
Background Polycystic ovary syndrome (PCOS) is an endocrine disorder, affecting women
of reproductive age. Ageratum conyzoïdes (AGC) is used traditionally in the treatment of …

Insights from molecular docking and molecular dynamics on the potential of vitexin as an antagonist candidate against lipopolysaccharide (LPS) for microglial …

MAF Yahaya, ARA Bakar, J Stanslas, N Nordin… - BMC …, 2021 - Springer
Background Neuroinflammation has been identified to be the key player in most
neurodegenerative diseases. If neuroinflammation is left to be unresolved, chronic …

Ficus deltoidea ameliorates biochemical, hormonal, and histomorphometric changes in letrozole-induced polycystic ovarian syndrome rats

MA Haslan, N Samsulrizal, N Hashim… - … Medicine and Therapies, 2021 - Springer
Background Insulin resistance and hormonal imbalances are key features in the
pathophysiology of polycystic ovarian syndrome (PCOS). We have previously shown that …