Atherosclerotic disease, such as myocardial infarction and stroke, is the number one killer
worldwide. Atherosclerosis is considered to be caused by multiple factors, including genetic …

The animal model deals with the species other than the human, as it can imitate the disease
progression, its' diagnosis as well as a treatment similar to human. Discovery of a drug …

The intracellular sensing protein termed NLRP3 (for NACHT, LRR, and PYD domains-
containing protein 3) forms a macromolecular structure called the NLRP3 inflammasome …

An ideal animal model of atherosclerosis resembles human anatomy and pathophysiology
and has the potential to be used in medical and pharmaceutical research to obtain results …

Obesity and its comorbidities, including type 2 diabetes and cardiovascular disease, are
straining our healthcare system, necessitating the development of novel strategies for weight …

Diet might affect male reproductive potential, but the biochemical mechanisms involved in
the modulation of sperm quality remain poorly understood. While a Western diet is …

Animal studies are a foundation for defining mechanisms of atherosclerosis and potential
targets of drugs to prevent lesion development or reverse the disease. In the current …

Herein, a wireless and soft smart contact lens that enables real‐time quantitative recording
of cholesterol in tear fluids for the monitoring of patients with hyperlipidemia using a …

Cardiovascular disease is the leading cause of death worldwide. Although investment in
drug discovery and development has been sky-rocketing, the number of approved drugs has …

High protein intake is common in western societies and is often promoted as part of a
healthy lifestyle; however, amino-acid-mediated mammalian target of rapamycin (mTOR) …