Neurogastroenterology is defined as neurology of the gastrointestinal tract, liver, gallbladder
and pancreas and encompasses control of digestion through the enteric nervous system …

Background Hirschsprung's disease (HSCR) is a serious congenital bowel disorder with a
prevalence of 1/5000. Currently, there is a lack of systematically developed guidelines to …

Disturbances of gastric, intestinal and colonic motor and sensory functions affect a large
proportion of the population worldwide, impair quality of life and cause considerable health …

The gastrointestinal tract contains its own set of intrinsic neuroglial circuits—the enteric
nervous system (ENS)—which detects and responds to diverse signals from the …

Objectives: Chronic intestinal pseudo-obstructive (CIPO) conditions are considered the most
severe disorders of gut motility. They continue to present significant challenges in clinical …

Constipation is broadly defined as an unsatisfactory defecation characterized by infrequent
stools, difficult stool passage or both. The common approach to the pathophysiology of …

Background Chronic intestinal pseudo‐obstruction (CIPO) represents the most severe form
of gastrointestinal dysmotility with debilitating and potentially lethal consequences …

Over the last 20 years, there has been increasing focus on the development of novel stem
cell based therapies for the treatment of disorders and diseases affecting the enteric nervous …

The enteric nervous system (ENS) is sometimes called the “second brain” because of the
diversity of neuronal cell types and complex, integrated circuits that permit the ENS to …

Functional gastrointestinal disorders range from highly prevalent, but generally benign
conditions, eg, functional dyspepsia and irritable bowel syndrome, to rare and potentially life …