Modulating aptamer function by copper (II)-mediated base pair formation

MH Heddinga, J Müller - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
Two aptamers, one for ATP and one for arginine, were modified using an artificial 2′-
dexoyribonucleoside based on the nucleobase surrogate imidazole-4-carboxylate. This …

Towards polymerase-mediated synthesis of artificial RNA–DNA metal base pairs

F Levi-Acobas, LK Mckenzie… - New Journal of Chemistry, 2022 - pubs.rsc.org
Metal-mediated base pairs are formed by the connection of two nucleobases via
coordination to a metal cation. The resulting metal-containing duplexes have been used in a …

Dynamic Structure and Stability of DNA Duplexes Bearing a Dinuclear Hg (II)-Mediated Base Pair

J Bachmann, I Schönrath, J Müller, NL Doltsinis - Molecules, 2020 - mdpi.com
Quantum mechanical (QM) and hybrid quantum mechanical/molecular mechanical (QM/MM)
molecular dynamics simulations of a recently reported dinuclear mercury (II)-mediated base …

Stable Hg (II)-mediated base pairs with a phenanthroline-derived nucleobase surrogate in antiparallel-stranded DNA

B Jash, J Müller - JBIC Journal of Biological Inorganic Chemistry, 2020 - Springer
Metal-mediated base pairs involving artificial nucleobases have emerged as a promising
means for the site-specific functionalization of nucleic acids with metal ions. In this context, a …

Light-induced formation of silver (I)-mediated base pairs in DNA: Possibilities and limitations

S Naskar, M Hebenbrock, J Müller - Inorganica Chimica Acta, 2020 - Elsevier
The applicability of the caged nucleoside C NPP (2′-deoxycytidine bearing an ortho-
nitrophenylpropyl group at the exocyclic N4 position) in the light-triggered formation of three …

Silver(I)-mediated base pairing involving an S-glycosidic GNA nucleoside analogue

I Schönrath, H Aukam, B Jasper-Peter… - … , Nucleotides & Nucleic …, 2021 - Taylor & Francis
Abstract The 4S–Ag (I)–C base pair (4S, 3-((2-(methylthio) pyrimidin-4-yl) thio) propane-1, 2-
diol; C, deoxycytidine) represents the first metal-mediated base pair comprising an S …

Triggering Copper (II)-Mediated Base Pair Formation by Light

S Naskar, J Müller - Inorganic Chemistry, 2021 - ACS Publications
Metal-mediated base pairs enable a site-specific incorporation of transition metal ions into
nucleic acid structures. The resulting nucleic acid–metal complex conjugates are of interest …

Modelos mesoscópicos para DNA mediado por metal e na presença de solventes que simulam o meio molecular

LG Silva - 2023 - repositorio.ufmg.br
Ácidos nucleicos, em especial DNA e RNA, têm importância biológica e tecnológica
inegável. Aqui, desenvolvemos dois projetos relacionados à estabilidade de ácidos …

Polymerase-mediated synthesis of artificial RNA-DNA metal base pairs

F Levi-Acobas, L McKenzie, M Hollenstein - 2021 - chemrxiv.org
Metal-mediated base pairs are formed by the connection of two nucleobases via
coordination to a metal cation. The resulting metal-containing duplexes have been used in a …

[PDF][PDF] RECOGNITION OF SINGLE-AND DOUBLE-STRANDED NUCLEIC ACIDS BY COVALENTLY MERCURATED OLIGONUCLEOTIDES

DU Ukale - utupub.fi
Metal-mediated base pairs have attracted considerable attention during the past decades for
their potential in bio-and nanotechnological applications. The introduction of metal ions into …