Clinical challenges in bone tissue engineering-A narrative review

AH Hoveidaei, M Sadat-Shojai, SS Nabavizadeh… - Bone, 2024 - Elsevier
Bone tissue engineering (BTE) has emerged as a promising approach to address large
bone defects caused by trauma, infections, congenital malformations, and tumors. This …

The Role of XBP1 in bone metabolism

W Lv, Y Zheng, J Jiao, Y Fu, T Xu, L Zhang… - Frontiers in …, 2023 - frontiersin.org
Bone is a dynamic organ that, once formed, undergoes a constant remodeling process that
includes bone resorption and synthesis. Osteoclasts and osteoblasts are primarily …

Endothelial to mesenchymal Notch signaling regulates skeletal repair

S Novak, H Tanigawa, V Singh, SH Root… - JCI …, 2024 - Am Soc Clin Investig
We present a transcriptomic analysis that provides a better understanding of regulatory
mechanisms within the healthy and injured periosteum. The focus of this work is on …

BMP2 induces osteogenic differentiation through ACKR3 in mesenchymal stem cells

J Liu, XT Yao, XL Feng, XZ Bai - Biochemical and Biophysical Research …, 2023 - Elsevier
In recent years, bone loss related diseases have attracted more and more attention, such as
osteoporosis and osteonecrosis of the femoral head exhibited symptoms of osteopenia or …

Recombinant Human Peptide Growth Factors, Bone Morphogenetic Protein-7 (rhBMP7), and Platelet-Derived Growth Factor-BB (rhPDGF-BB) for Osteoporosis …

TG Reis, AMS Del Colletto, LAS Silva, BAA Koga… - Biomolecules, 2024 - mdpi.com
Bone morphogenetic protein (BMP) and platelet-derived growth factor (PDGF) are known to
regulate/stimulate osteogenesis, playing vital roles in bone homeostasis, rendering them …

Periosteum Containing Implicit Stem Cells: A Progressive Source of Inspiration for Bone Tissue Regeneration

X Zhang, C Deng, S Qi - International Journal of Molecular Sciences, 2024 - mdpi.com
The periosteum is known as the thin connective tissue covering most bone surfaces. Its
extrusive bone regeneration capacity was confirmed from the very first century-old studies …

[HTML][HTML] Regional Gene Therapy for Bone Tissue Engineering: A Current Concepts Review

MC Gallo, A Elias, J Reynolds, JR Ball, JR Lieberman - Bioengineering, 2025 - mdpi.com
The management of segmental bone defects presents a complex reconstruction challenge
for orthopedic surgeons. Current treatment options are limited by efficacy across the …

Platelets in Vascular Calcification: A Comprehensive Review of Platelet-Derived Extracellular Vesicles, Protein Interactions, Platelet Function Indices, and their Impact …

Y He, Q Zhang, L Pan, H Yang, T Liu… - … in Thrombosis and …, 2024 - thieme-connect.com
Vascular calcification (VC) commonly accompanies the development of atherosclerosis,
defined by the accumulation of calcium in the arterial wall, potentially leading to stroke and …

Application of Titanium Mesh in the Early Treatment of Flail Chest

G Liu, L Zhou, C Li, J Cao, Y Zhang… - International Journal …, 2024 - Wiley Online Library
Objective: To investigate the effect of the titanium mesh on flail chest and bone healing from
clinical and animal experiments. Methods: Clinical experiment: 24 patients with flail chests in …

内皮细胞特异性骨形态发生蛋白2 对血管新生的影响: 生物信息学分析和实验验证

燕茹, 王凯茹, 张飞燕, 贾绍斌, 丛广志 - 中国组织工程研究, 2025 - cjter.com
内皮细胞特异性骨形态发生蛋白2 对血管新生的影响:生物信息学分析和实验验证 Page 1
Chinese Journal of Tissue Engineering Research|Vol 29|No.1|January 2025|103 中国组织 …