Walking is a simple form of exercise, widely promoted for its health benefits. Self-reported
walking pace has been associated with a range of cardiorespiratory and cancer outcomes …

Cholesterol is an important precursor of many endogenous molecules. Disruption of
cholesterol homeostasis can cause many pathological changes, leading to liver and …

The aim of the study was directed at studying the sex-specific features of the correlation
between genome-wide association studies (GWAS)-noticeable polymorphisms and …

Background Exposure to environmental endocrine disrupting chemicals (EDCs) may play an
important role in the epidemic of metabolic diseases. Epigenetic alterations may functionally …

The aim of this study was to explore the effects of pre-pregnancy overweight/obesity on the
pattern of association of hypertension susceptibility genes with preeclampsia (PE). Ten …

Hypertension is a disease associated with epigenetic aging. However, the pathogenic
mechanism underlying this relationship remains unclear. We aimed to characterize the …

The aim of this case-control replicative study was to investigate the link between GWAS-
impact for arterial hypertension (AH) and/or blood pressure (BP) gene polymorphisms and …

Background Hypertension, clinically defined by elevated blood pressure (BP), is an
important cause of mortality and morbidity worldwide. Many risk factors for hypertension are …

The pharmacological management of musculoskeletal pain starts with NSAIDs, followed by
weak or strong opioids until the pain is under control. However, the treatment outcome is …

Purpose To identify novel susceptibility loci for retinal vascular tortuosity, to better
understand the molecular mechanisms modulating this trait, and reveal causal relationships …