Molecular mechanisms of hepatocarcinogenesis following sustained virological response in patients with chronic hepatitis C virus infection
CN Hayes, P Zhang, Y Zhang, K Chayama - Viruses, 2018 - mdpi.com
Despite the success of direct-acting antiviral (DAA) agents in treating chronic hepatitis C
virus (HCV) infection, the number of cases of HCV-related hepatocellular carcinoma (HCC) …
virus (HCV) infection, the number of cases of HCV-related hepatocellular carcinoma (HCC) …
Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors
MN Huang, W Yu, WW Teoh, M Ardin… - Genome …, 2017 - genome.cshlp.org
Aflatoxin B1 (AFB1) is a mutagen and IARC (International Agency for Research on Cancer)
Group 1 carcinogen that causes hepatocellular carcinoma (HCC). Here, we present the first …
Group 1 carcinogen that causes hepatocellular carcinoma (HCC). Here, we present the first …
Adipose-enriched peri-tumoral stroma, in contrast to myofibroblast-enriched stroma, prognosticates poorer survival in breast cancers
HSH Lau, VKM Tan, BKT Tan, Y Sim, J Quist… - NPJ Breast …, 2023 - nature.com
Despite our understanding of the genetic basis of intra-tumoral heterogeneity, the role of
stromal heterogeneity arising from an altered tumor microenvironment in affecting …
stromal heterogeneity arising from an altered tumor microenvironment in affecting …
Longitudinal metabolic imaging of hepatocellular carcinoma in transgenic mouse models identifies acylcarnitine as a potential biomarker for early detection
J Yaligar, WW Teoh, R Othman, SK Verma… - Scientific Reports, 2016 - nature.com
The cumulative effects of hepatic injury due to hepatitis B virus (HBV) infections and aflatoxin-
B1 (AFB1) exposure are the major risk factors of HCC. Understanding early metabolic …
B1 (AFB1) exposure are the major risk factors of HCC. Understanding early metabolic …
HAfTs are novel lncRNA transcripts from aflatoxin exposure
BA Merrick, JS Chang, DP Phadke, MA Bostrom… - PLoS …, 2018 - journals.plos.org
The transcriptome can reveal insights into precancer biology. We recently conducted RNA-
Seq analysis on liver RNA from male rats exposed to the carcinogen, aflatoxin B1 (AFB1), for …
Seq analysis on liver RNA from male rats exposed to the carcinogen, aflatoxin B1 (AFB1), for …
Gene silencing of Nox4 by CpG island methylation during hepatocarcinogenesis in rats
GS López-Álvarez, TK Wojdacz… - Biology …, 2017 - journals.biologists.com
The association between the downregulation of genes and DNA methylation in their CpG
islands has been extensively studied as a mechanism that favors carcinogenesis. The …
islands has been extensively studied as a mechanism that favors carcinogenesis. The …
Aspergillus
L Kredics, J Varga, R Jayasudha… - Laboratory Models for …, 2017 - taylorfrancis.com
This chapter provides an overview about the laboratory models used to study Aspergillus
mycotoxicoses, with a special focus on the most recent publications applying rodent models …
mycotoxicoses, with a special focus on the most recent publications applying rodent models …