The suprachiasmatic nucleus (SCN) of the hypothalamus is remarkable. Despite numbering
only about 10,000 neurons on each side of the third ventricle, the SCN is our principal …

The suprachiasmatic nucleus (SCN) is the principal circadian clock of the brain, directing
daily cycles of behavior and physiology. SCN neurons contain a cell-autonomous …

The hypothalamus is a central regulator of many innate behaviors essential for survival, but
the molecular mechanisms controlling hypothalamic patterning and cell fate specification …

Folate is vital for fetal development. Periconceptional folic acid supplementation and food
fortification are recommended to prevent neural tube defects. Mechanisms whereby …

In mammals, the central circadian clock is located in the suprachiasmatic nucleus (SCN) of
the hypothalamus. Individual SCN cells exhibit intrinsic oscillations, and their circadian …

Circadian timekeeping allows appropriate temporal regulation of an organism's internal
metabolism to anticipate and respond to recurrent daily changes in the environment …

Precise timing in hormone release from the hypothalamus, the pituitary and ovary is critical
for fertility. Hormonal release patterns of the reproductive axis are regulated by a feedback …

The finding that animals with circadian gene mutations exhibit diet-induced obesity and
metabolic syndrome with hypoinsulinemia revealed a distinct role for the clock in the brain …

The hypothalamus, which regulates fundamental aspects of physiological homeostasis and
behavior, is a brain region that exhibits highly conserved anatomy across vertebrate …

In mammals, the suprachiasmatic nucleus (SCN) of the hypothalamus coordinates daily
rhythms including sleep–wake, hormone release, and gene expression. The cells of the …