Protein synthesis is one of the major targets in the cell for antibiotics. This review endeavors
to provide a comprehensive “post-ribosome structure” A–Z of the huge diversity of antibiotics …

A central question in cell and developmental biology is how the information encoded in the
genome is differentially interpreted to generate a diverse array of cell types. A growing body …

Deciphering physiological changes that mediate transition of Mycobacterium tuberculosis
between replicating and nonreplicating states is essential to understanding how the …

Escherichia coli (E. coli) mazEF is a stress-induced toxin-antitoxin (TA) module. The toxin
MazF is an endoribonuclease that cleaves single-stranded mRNAs at ACA sequences …

Bacterial mRNAs are organized into operons consisting of discrete open reading frames
(ORFs) in a single polycistronic mRNA. Individual ORFs on the mRNA are differentially …

Regulation of translation initiation is well appropriate to adapt cell growth in response to
stress and environmental changes. Many bacterial mRNAs adopt structures in their 5 …

Abstract Background Differential RNA-Seq (dRNA-Seq) is a recently developed method of
performing primary transcriptome analyses that allows for the genome-wide mapping of …

Several studies have shown that AgNPs can be toxic to phytoplankton, but the underlying
cellular mechanisms still remain largely unknown. Here we studied the toxicity and …

Quality control of ribosomes is critical for cellular function since protein mistranslation leads
to severe physiological consequences. We report evidence of a previously unrecognized …

Translation initiation is a crucial step of protein synthesis which largely defines how the
composition of the cellular transcriptome is converted to the proteome and controls the …