The enigmatic function of PARP1: from PARylation activity to PAR readers
T Kamaletdinova, Z Fanaei-Kahrani, ZQ Wang - Cells, 2019 - mdpi.com
Poly (ADP-ribosyl) ation (PARylation) is catalysed by poly (ADP-ribose) polymerases
(PARPs, also known as ARTDs) and then rapidly removed by degrading enzymes. Poly …
(PARPs, also known as ARTDs) and then rapidly removed by degrading enzymes. Poly …
Protein–protein interactions: scoring schemes and binding affinity
MM Gromiha, K Yugandhar, S Jemimah - Current opinion in structural …, 2017 - Elsevier
Highlights•Reviewed scoring schemes and conformational sampling for protein–protein
complex structure prediction.•Discussed the database for binding affinity of complexes and …
complex structure prediction.•Discussed the database for binding affinity of complexes and …
Effect of atmospheric cold plasma on structure, interfacial and emulsifying properties of Grass pea (Lathyrus sativus L.) protein isolate
HM Mehr, A Koocheki - Food Hydrocolloids, 2020 - Elsevier
Abstract Structure and emulsifying properties of Grass pea (Lathyrus sativus) protein isolate
(GPPI) were investigated as function of cold plasma treatment at two voltages (9.4 and 18.6 …
(GPPI) were investigated as function of cold plasma treatment at two voltages (9.4 and 18.6 …
Potential application of DBD Plasma Technique for modifying structural and physicochemical properties of Soy Protein Isolate
H Sharafodin, N Soltanizadeh - Food Hydrocolloids, 2022 - Elsevier
The present study was designed and implemented to modify soy protein isolate (SPI) using
dielectric barrier discharge (DBD) plasma and investigate the effects of this treatment on the …
dielectric barrier discharge (DBD) plasma and investigate the effects of this treatment on the …
Spatial organization of hydrophobic and charged residues affects protein thermal stability and binding affinity
What are the molecular determinants of protein–protein binding affinity and whether they are
similar to those regulating fold stability are two major questions of molecular biology, whose …
similar to those regulating fold stability are two major questions of molecular biology, whose …
DDAffinity: predicting the changes in binding affinity of multiple point mutations using protein 3D structure
G Yu, Q Zhao, X Bi, J Wang - Bioinformatics, 2024 - academic.oup.com
Motivation Mutations are the crucial driving force for biological evolution as they can disrupt
protein stability and protein–protein interactions which have notable impacts on protein …
protein stability and protein–protein interactions which have notable impacts on protein …
Emerging concepts in TCR specificity: rationalizing and (maybe) predicting outcomes
T cell specificity emerges from a myriad of processes, ranging from the biological pathways
that control T cell signaling to the structural and physical mechanisms that influence how …
that control T cell signaling to the structural and physical mechanisms that influence how …
Interplay among structural stability, plasticity, and energetics determined by conformational attuning of flexible loops in PD-1
The dynamics and plasticity of the PD-1/PD-L1 axis are the bottlenecks for the discovery of
small-molecule antagonists to perturb this interaction interface significantly. Understanding …
small-molecule antagonists to perturb this interaction interface significantly. Understanding …
Computational Approaches to Predict Protein–Protein Interactions in Crowded Cellular Environments
Investigating protein–protein interactions is crucial for understanding cellular biological
processes because proteins often function within molecular complexes rather than in …
processes because proteins often function within molecular complexes rather than in …
The ins and outs of RAS effector complexes
RAS oncogenes are among the most commonly mutated proteins in human cancers. They
regulate a wide range of effector pathways that control cell proliferation, survival …
regulate a wide range of effector pathways that control cell proliferation, survival …