Orexin peptides comprise two neuropeptides, orexin A and orexin B, that bind two G-protein
coupled receptors (GPCRs), orexin receptor 1 (OXR1) and orexin receptor 2 (OXR2) …

Orexins are highly involved in regulating the circadian rhythm, the brain's reward
mechanism, and the neuroendocrine response to stress. The disruption of orexin regulation …

Those with a negative experience of psychosocial stress during the early stage of life not
only have a high susceptibility of the psychiatric disorder in all phases of their life span, but …

Orexin A and B, also known as hypocretin 1 and 2, are excitory neuropeptides synthesized
in the perifornical and lateral hypothalamic areas. Following their discovery in 1998, orexins …

Orexin–a neuropeptide–is extensively distributed in the central nervous system and is
involved in the regulation of diverse physiological functions and behaviors. Orexin is …

Objective To investigate the efficacy and mechanism of action of Compound Chaijin Jieyu
Tablets (复方柴金解郁片, CCJJYT) in rats with insomnia complicated with depression …

Advances in Clinical Chemistry, Volume 107, the latest installment in this internationally
acclaimed series, contains chapters authored by world-renowned clinical laboratory …

Nepřiznivé události vyvolávající stres během postnatálního období života mohou změnit
normální vývoj mozku a neuroendokrinního systému a zvýšit náchylnost jedince vůči různým …