The complement system is a key component of innate immunity. More than 45 genes
encoding the proteins of complement components or their isotypes and subunits, receptors …

Serum complement cascade, a part of innate immunity required for host protection against
invading pathogens, is also a mediator of various forms of disease and injury. It is activated …

Introduction A role for mannose binding lectin (MBL) in autoimmune diseases has been
demonstrated earlier and elevated level of MBL has been shown in systemic lupus …

Background Mannose-binding lectin (MBL) is a member of innate immunity and acts with
MASP (MBL-associated serine protease) to activate the lectin pathway of the complement …

As imunodeficiências primárias (IDP) representam um grupo heterogêneo de doenças
resultantes de defeitos hereditários no desenvolvimento, na maturação e na função normal …

Introduction Deep vein thrombosis (DVT) originates in the valvular sinuses of large veins in
a local milieu characterized by stasis and severe hypoxia. This may induce complement-and …

Objectives Mannose binding lectin (MBL) gene single nucleotide polymorphisms have been
associated with systemic lupus erythematosus (SLE) risk with inconsistent results. This study …

Introduction Rheumatoid arthritis (RA) is a commonly occurring systemic inflammatory auto
immune disease and is believed to be associated with genetic factors. The innate immune …

Methods: The MBL alleles [-550,-221,+ 4, Codon 52, Codon 54 and Codon 57] were studied
by PCR-RFLP (restriction fragment length polymorphism) method in 100 SLE patients …

As imunodeficiências primárias (IDP) representam um grupo heterogêneo de doenças
resultantes de defeitos hereditários no desenvolvimento, na maturação e na função normal …