Aim The ideal route of tranexamic acid (TXA) administration in total hip arthroplasty (THA) or
total knee arthroplasty (TKA) remains controversial. This study aims to identify the optima …

Background A comprehensive review of the current evidence investigating the potential
therapeutic effects of tranexamic acid (TXA) and its safety in foot and ankle surgery is …

Background Tranexamic acid (TXA) is an antifibrinolytic agent applied in orthopedic surgery
and has been proven to reduce post-surgery infection rates. We previously showed that TXA …

Abstract Background/Objective: Effective hemostasis has the potential to reduce
inflammation and pain, leading to potential benefits in the early rehabilitation of patients who …

Background Hip and knee replacement surgery is a well‐established means of improving
quality of life, but is associated with a significant risk of bleeding. One‐third of people are …

Abstract Total Joint Arthroplasty (TJA) is a major surgery performed for patients who suffer
from severe joint destruction. It is so important to reduce the blood loss in the TJA surgery to …

Objectives: We aimed to assess the most effective route for Tranexamic acid (TXA)
administration among Intraarticular (IA), Intravenous (IV), and combined IA/IV for Total Knee …

Purpose/objectives This study was conducted to compare the efficacy of preoperative
intravenous (IV) and intraoperative topical administration of tranexamic acid versus …

Objective: We perform this protocol for randomized controlled trial to compare the efficacy of
intrathecal morphine and local infiltration anesthesia (LIA) in the treatment of the …

Introduction Total knee arthroplasty (TKA) poses challenges due to significant blood loss,
often necessitating blood transfusions and leading to complications. Various methods exist …