The DNA damage response (DDR) is a complex signal transduction network that is activated
when endogenous or exogenous genotoxins damage or interfere with the replication of …

Xanthohumol is a cancer chemopreventive agent that can interfere with the initiation,
promotion, and progression phase of carcinogenesis via a variety of inhibitory mechanisms …

Barking up the right tree: advancing our understanding and t... : Current Opinion in
Hematology Barking up the right tree: advancing our understanding and treatment of …

Treatment of neoplastic diseases in companion animals is one of the most important
problems of modern veterinary medicine. Given the growing interest in substances of natural …

This work presents the chemo-enzymatic Baeyer–Villiger oxidation of α-
benzylcyclopentanones in ester solvents as well as deep eutectic solvents (DES). In the first …

We established a canine natural killer (NK)‐type cell line called CNK‐89 derived from a dog
with NK cell neoplasia. Immunophenotyping analysis showed positive staining for CD5 …

Background Dogs present a significant opportunity for studies in comparative oncology.
However, the study of cancer biology phenomena in canine cells is currently limited by …

Ataxia telangiectasia and Rad3‐related (ATR) kinase is one of the main regulators of cell
response to DNA damage and replication stress. Effectiveness of ATR targeting in human …

Herbal formulations have been used in ethnomedicine and pharmacy around the world for
thousands of years. One of them is Jerusalem Balsam (JB), which came into use in the …

Four stereoisomers of δ-iodo-γ-lactones with p-isopropylphenyl substituent at β-position: cis-
(4R, 5R, 6S)-1, cis-(4S, 5S, 6R)-2, trans-(4R, 5S, 6R)-3, trans-(4S, 5R, 6S)-4 with proved …