The incidence of inflammatory bowel diseases (IBD) emerged with Westernisation of dietary
habits worldwide. Crohn's disease and ulcerative colitis are chronic debilitating conditions …

The intestinal tract is lined by a single layer of columnar epithelial cells that forms a dynamic,
permeable barrier allowing for selective absorption of nutrients, while restricting access to …

Integration of the intestinal epithelium and the mucosal immune system is critical for gut
homeostasis. The intestinal epithelium is a functional barrier that secludes luminal content …

Polymorphonuclear leukocytes or neutrophils play a critical role in the maintenance of
intestinal homeostasis. They have elegant defense mechanisms to eliminate microbes that …

The acute respiratory distress syndrome (ARDS) causes 40% mortality in approximately
200,000 critically ill patients annually in the United States. ARDS is caused by protein-rich …

The human gut microflora is important in regulating host inflammatory responses and in
maintaining immune homeostasis. The cellular and molecular bases of these actions are …

Mucosal repair is a complex event that immediately follows acute injury induced by ischemia
and noxious luminal contents such as bile. In the small intestine, villous contraction is the …

Inflammatory bowel diseases (IBD), comprising of ulcerative colitis and Crohn's disease, are
inflammatory disorders of the gastrointestinal tract characterized by chronically relapsing …

We recently uncovered two new families of potent docosahexaenoic acid-derived mediators,
termed D series resolvins (Rv; resolution phase interaction products) and protectins. Here …

Inflammatory bowel disease (IBD) consisting of ulcerative colitis (UC) and Crohn's (CD)
typically displays a waxing and waning course punctuated by disease flares that are …