Diagnosis of neonatal sepsis: the past, present and future

IH Celik, M Hanna, FE Canpolat, M Pammi - Pediatric research, 2022 - nature.com
Sepsis remains a significant cause of neonatal mortality and morbidity, especially in low-and
middle-income countries. Neonatal sepsis presents with nonspecific signs and symptoms …

Diagnosis of neonatal sepsis: the role of inflammatory markers

J Eichberger, E Resch, B Resch - Frontiers in Pediatrics, 2022 - frontiersin.org
This is a narrative review on the role of biomarkers in the diagnosis of neonatal sepsis. We
describe the difficulties to obtain standardized definitions in neonatal sepsis and discuss the …

Neonatal sepsis: a review of pathophysiology and current management strategies

MA Glaser, LM Hughes, A Jnah… - Advances in neonatal …, 2021 - journals.lww.com
Background: Early-onset sepsis, occurring within 72 hours of birth, and late-onset sepsis,
occurring after this time period, present serious risks for neonates. While culture-based …

Presepsin for the diagnosis of neonatal early-onset sepsis: a systematic review and meta-analysis

C Poggi, E Lucenteforte, D Petri, S De Masi… - JAMA …, 2022 - jamanetwork.com
Importance Neonatal early-onset sepsis (EOS) is a severe disease, particularly in preterm
infants. Timely diagnosis can be challenging owing to unspecific presentation and …

Reliability of interleukin-6 alone and in combination for diagnosis of early onset neonatal sepsis: Systematic review

J Eichberger, B Resch - Frontiers in Pediatrics, 2022 - frontiersin.org
Neonatal sepsis is a major cause of morbidity and mortality in both preterm and term infants.
Early-onset neonatal sepsis (EONS) presents within the first 72 h of life. Diagnosis is difficult …

Biomarkers of neonatal sepsis: where we are and where we are going

G Boscarino, R Migliorino, G Carbone, G Davino… - Antibiotics, 2023 - mdpi.com
Neonatal sepsis is a bacterial bloodstream infection leading to severe clinical manifestations
frequently associated with death or irreversible long-term deficits. Antibiotics are the drug of …

Biomarkers for point-of-care diagnosis of sepsis

A Teggert, H Datta, Z Ali - Micromachines, 2020 - mdpi.com
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection. In 2017, almost 50 million cases of sepsis were recorded worldwide …

Fighting antimicrobial resistance in neonatal intensive care units: rational use of antibiotics in neonatal sepsis

D Rallis, V Giapros, A Serbis, C Kosmeri, M Baltogianni - Antibiotics, 2023 - mdpi.com
Antibiotics are the most frequently prescribed drugs in neonatal intensive care units (NICUs)
due to the severity of complications accompanying neonatal sepsis. However, antimicrobial …

Advancement in biomarker based effective diagnosis of neonatal sepsis

N Gopal, N Chauhan, U Jain, SK Dass… - Artificial Cells …, 2023 - Taylor & Francis
Neonatal sepsis is considered as alarming medical emergency and becomes the common
global reason of neonatal mortality. Non-specific symptoms and limitations of conventional …

Green Synthesis of Silver Nanoparticles Using Spilanthes acmella Leaf Extract and its Antioxidant-Mediated Ameliorative Activity against Doxorubicin-Induced …

F Lalsangpuii, SL Rokhum, F Nghakliana… - ACS …, 2022 - ACS Publications
Green synthesis of metal nanoparticles is a rapidly growing research area in the field of
nanotechnology because of their biomedical applications. This study describes the …