A Systematic Review on Ketamine and Esketamine for Treatment-Resistant Depression and Suicidality in Adolescents: A New Hope?
S Pardossi, A Fagiolini, S Scheggi, A Cuomo - Children, 2024 - mdpi.com
Treating depression in adolescents is a significant challenge, and major depressive disorder
(MDD) with suicidal ideation and treatment-resistant depression (TRD) are common and …
(MDD) with suicidal ideation and treatment-resistant depression (TRD) are common and …
Esketamine alleviates LPS-induced depression-like behavior by activating Nrf2-mediated anti-inflammatory response in adolescent mice
X Ma, S Xue, H Ma, Y Zhang, Y Meng, H Chen, H Yu… - Neuroscience, 2025 - Elsevier
Background The mechanisms underlying esketamine's therapeutic effects remain elusive.
The study aimed to explore the impact of single esketamine treatment on LPS-induced …
The study aimed to explore the impact of single esketamine treatment on LPS-induced …
Ketamine treatment in youth for fast reduction of suicidality and engagement in psychotherapy: A randomized placebo-controlled trial protocol
NA Reilly-Harrington, T Falcone, DA Jobes… - Contemporary Clinical …, 2025 - Elsevier
Background Suicide is a leading cause of death in young persons. While ketamine has
demonstrated rapid anti-suicidal effects, its safety and efficacy in youth has not been fully …
demonstrated rapid anti-suicidal effects, its safety and efficacy in youth has not been fully …
Intranasal dantrolene nanoparticles inhibit lipopolysaccharide-induced depression and anxiety behavior in mice
J Liu, Y Lu, P Bhuiyan, J Gruttner, LS Louis, Y Yi… - bioRxiv, 2024 - biorxiv.org
This study investigates the therapeutic effectiveness of intranasal dantrolene nanoparticles
pretreatment to inhibit lipopolysaccharide (LPS)-induced pathological inflammation and …
pretreatment to inhibit lipopolysaccharide (LPS)-induced pathological inflammation and …
Renaissance of Ketamine
K Kocur, K Camlet, A Ziobro, M Ziomek… - Prospects in …, 2024 - prospects.wum.edu.pl
The history of ketamine began in the 1960s. Ketamine is a specific anesthetic drug that
exhibits analgesia, has a stabilizing impact on the cardiovascular system and does not …
exhibits analgesia, has a stabilizing impact on the cardiovascular system and does not …