Subtle brain developmental abnormalities in the pathogenesis of juvenile myoclonic epilepsy
M Gilsoul, T Grisar, AV Delgado-Escueta… - Frontiers in Cellular …, 2019 - frontiersin.org
Juvenile myoclonic epilepsy (JME), a lifelong disorder that starts during adolescence, is the
most common of genetic generalized epilepsy syndromes. JME is characterized by …
most common of genetic generalized epilepsy syndromes. JME is characterized by …
[HTML][HTML] Neurocysticercosis-related seizures: Imaging biomarkers
Neurocysticercosis (NCC)—a parasitic CNS infection endemic to developing nations—has
been called the leading global cause of acquired epilepsy yet remains understudied. It is …
been called the leading global cause of acquired epilepsy yet remains understudied. It is …
Abnormal hippocampal structure and function in juvenile myoclonic epilepsy and unaffected siblings
Juvenile myoclonic epilepsy is the most common genetic generalized epilepsy syndrome,
characterized by a complex polygenetic aetiology. Structural and functional MRI studies …
characterized by a complex polygenetic aetiology. Structural and functional MRI studies …
Probabilistic mapping of thalamic nuclei and thalamocortical functional connectivity in idiopathic generalised epilepsy
Y Chen, N Fallon, BAK Kreilkamp, C Denby… - Human Brain …, 2021 - Wiley Online Library
It is well established that abnormal thalamocortical systems play an important role in the
generation and maintenance of primary generalised seizures. However, it is currently …
generation and maintenance of primary generalised seizures. However, it is currently …
Alterations in the hippocampal‐thalamic pathway underlying secondarily generalized tonic–clonic seizures in mesial temporal lobe epilepsy: A diffusion tensor …
Objective The epileptogenic network underlying secondarily generalized tonic–clonic
seizures (sGTCS) in mesial temporal lobe epilepsy (mTLE) is not well understood. Here, we …
seizures (sGTCS) in mesial temporal lobe epilepsy (mTLE) is not well understood. Here, we …
[HTML][HTML] On the potential for mapping apparent neural soma density via a clinically viable diffusion MRI protocol
Diffusion MRI is a valuable tool for probing tissue microstructure in the brain noninvasively.
Today, model-based techniques are widely available and used for white matter …
Today, model-based techniques are widely available and used for white matter …
Impaired topological properties of gray matter structural covariance network in epilepsy children with generalized tonic–clonic seizures: a graph theoretical analysis
Modern network science has provided exciting new opportunities for understanding the
human brain as a complex network of interacting regions. The improved knowledge of …
human brain as a complex network of interacting regions. The improved knowledge of …
Neuroimaging and thalamic connectomics in epilepsy neuromodulation
Neuromodulation is an increasingly utilized therapy for the treatment of people with drug-
resistant epilepsy. To date, the most common and effective target has been the thalamus …
resistant epilepsy. To date, the most common and effective target has been the thalamus …
[HTML][HTML] Quantitative MRI susceptibility mapping reveals cortical signatures of changes in iron, calcium and zinc in malformations of cortical development in children …
Objective Malformations of cortical development (MCD), including focal cortical dysplasia
(FCD), are the most common cause of drug-resistant focal epilepsy in children …
(FCD), are the most common cause of drug-resistant focal epilepsy in children …
Thalamohippocampal atrophy in focal epilepsy of unknown cause at the time of diagnosis
NJ Leek, M Neason, BAK Kreilkamp… - European journal of …, 2021 - Wiley Online Library
Background and purpose Patients with chronic focal epilepsy may have atrophy of brain
structures important for the generation and maintenance of seizures. However, little research …
structures important for the generation and maintenance of seizures. However, little research …