Vaccines against mpox: MVA-BN and LC16m8

JD Grabenstein, A Hacker - Expert Review of Vaccines, 2024 - Taylor & Francis
Introduction Global outbreaks involving mpox clade IIb began in mid-2022. Today, clade IIb
and clade I outbreaks continue. Reliable mpox vaccines can prevent serious mpox disease …

Paediatric, maternal, and congenital mpox: a systematic review and meta-analysis

NS Clemente, C Coles, ES Paixao… - The Lancet Global …, 2024 - thelancet.com
Background Although mpox has been detected in paediatric populations in central and west
Africa for decades, evidence synthesis on paediatric, maternal, and congenital mpox, and …

Monkeypox virus-infected individuals mount comparable humoral immune responses as Smallpox-vaccinated individuals

AD Otter, S Jones, B Hicks, D Bailey, H Callaby… - Nature …, 2023 - nature.com
In early 2022, a cluster of monkeypox virus (MPXV) infection (mpox) cases were identified
within the UK with no prior travel history to MPXV-endemic regions. Subsequently, case …

Concurrent outbreaks of mpox in Africa—an update

CG Beiras, E Malembi, R Escrig-Sarreta, S Ahuka… - The Lancet, 2025 - thelancet.com
In this Review, we examine the concurrent outbreaks of mpox in Africa, focusing on clade
1a, the newly emerged clade 1b, and clade 2b lineage A, and how they differ from the 2022 …

[PDF][PDF] Advancements in Mpox Vaccine Development: A Comprehensive Review of Global Progress and Recent Data

Z Yuqian, H Yize, W Wenling… - Biomedical and …, 2024 - besjournal.com
Since May 2022, a severe global Mpox epidemic has underscored the urgent need for a
preventative vaccine. On September 16, 2022, the mainland of China reported its first case …

Hidden in plain sight: the threat of mpox to children and adolescents

NS Clemente, K Le Doare, E Mupere… - The Lancet Child & …, 2024 - thelancet.com
In August 2024, WHO declared mpox a Public Health Emergency of International Concern
for the second time in 2 years in response to a surge in cases driven by the novel clade I …

Rapid development of double-hit mRNA antibody cocktail against orthopoxviruses

H Chi, SQ Zhao, RY Chen, XX Suo, RR Zhang… - … and Targeted Therapy, 2024 - nature.com
The Orthopoxvirus genus, especially variola virus (VARV), monkeypox virus (MPXV),
remains a significant public health threat worldwide. The development of therapeutic …

[HTML][HTML] Monkeypox virus (MPXV): A Brief account of global spread, epidemiology, virology, clinical features, pathogenesis, and therapeutic interventions

MA Islam, J Mumin, MM Haque, MA Haque, A Khan… - Infectious Medicine, 2023 - Elsevier
The largest MPXV outbreak of the 21st century occurred in 2022, which caused epidemics in
many countries. According to WHO, physical contact with infected persons, contaminated …

[PDF][PDF] Conquering Mpox: A Comprehensive Public Health Strategy for Addressing Mpox and Poxvirus Infections in Nigeria–Understanding Global Trends …

CO Elemuwa, MO Raimi, M Ainu, TC Adias… - JMIR …, 2024 - researchgate.net
Background: The growing global emphasis on combating infectious diseases has
highlighted the need for detailed analyses of outbreak patterns over time. Mpox, formerly …

Assessment of MpoxPlex, a high-throughput and multiplexed immunoassay: a diagnostic accuracy study

S Jones, B Hicks, H Callaby, D Bailey… - The Lancet …, 2025 - thelancet.com
Summary Background In May, 2022, the first global outbreak of mpox (formerly known as
monkeypox) occurred. In response, public health agencies in the UK have made smallpox …