Disorder and sequence repeats in hub proteins and their implications for network evolution

Z Dosztanyi, J Chen, AK Dunker, I Simon… - Journal of proteome …, 2006 - ACS Publications
Protein interaction networks display approximate scale-free topology, in which hub proteins
that interact with a large number of other proteins determine the overall organization of the …

Challenges in network science: Applications to infrastructures, climate, social systems and economics

S Havlin, DY Kenett, E Ben-Jacob, A Bunde… - The European Physical …, 2012 - Springer
Network theory has become one of the most visible theoretical frameworks that can be
applied to the description, analysis, understanding, design and repair of multi-level complex …

Self-emergence of knowledge trees: Extraction of the Wikipedia hierarchies

L Muchnik, R Itzhack, S Solomon, Y Louzoun - Physical Review E—Statistical …, 2007 - APS
The rapid accumulation of knowledge and the recent emergence of new dynamic and
practically unmoderated information repositories have rendered the classical concept of the …

An optimal algorithm for counting network motifs

R Itzhack, Y Mogilevski, Y Louzoun - Physica A: Statistical Mechanics and …, 2007 - Elsevier
Network motifs are small connected sub-graphs occurring at significantly higher frequencies
in a given graph compared with random graphs of similar degree distribution. Recently …

Growth network models with random number of attached links

S Sidorov, S Mironov - Physica A: Statistical Mechanics and Its Applications, 2021 - Elsevier
In the process of many real networks' growth, each new node joins a few existing nodes, the
number of which is unknown in advance. However, classical network growth models …

Power law distribution defines structural disorder as a structural element directly linked with function

P Tompa, L Kalmar - Journal of Molecular Biology, 2010 - Elsevier
Although intrinsically disordered proteins are prevalent and functionally important, it has
never been asked whether structural disorder should be considered as a separate structural …

Rank-based edge reconstruction for scale-free genetic regulatory networks

G Chen, P Larsen, E Almasri, Y Dai - BMC bioinformatics, 2008 - Springer
Background The reconstruction of genetic regulatory networks from microarray gene
expression data has been a challenging task in bioinformatics. Various approaches to this …

Comparative analysis of the transcription-factor gene regulatory networks of E. coli and S. cerevisiae

L Guzmán-Vargas, M Santillán - BMC systems biology, 2008 - Springer
Background The regulatory interactions between transcription factors (TF) and regulated
genes (RG) in a species genome can be lumped together in a single directed graph. The …

Friendship paradox in growth networks: analytical and empirical analysis

SP Sidorov, SV Mironov, AA Grigoriev - Applied Network Science, 2021 - Springer
Many empirical studies have shown that in social, citation, collaboration, and other types of
networks in real world, the degree of almost every node is less than the average degree of …

Genetic regulatory network models of biological clocks: Evolutionary history matters

JF Knabe, CL Nehaniv, MJ Schilstra - 2008 - direct.mit.edu
We study the evolvability and dynamics of artificial genetic regulatory networks (GRNs), as
active control systems, realizing simple models of biological clocks that have evolved to …