Nanomedicine and nanotheranostics: special focus on imaging of anticancer drugs induced cardiac toxicity

A Setia, RR Challa, B Vallamkonda, P Satti… - …, 2024 - pmc.ncbi.nlm.nih.gov
Cardiotoxicity, the often-overlooked second leading cause of death in cancer patients, has
been associated with certain anticancer drugs. These drugs can induce cardiac damage …

[HTML][HTML] How to define and manage low-risk drug allergy labels

AM Copaescu, L Li, KG Blumenthal… - The Journal of Allergy and …, 2024 - Elsevier
Risk stratification in drug allergy implies that specific risk categories (eg, low, moderate, and
high) classify historical drug hypersensitivity reactions. These risk categories can be based …

FATS inhibits the Wnt pathway and induces apoptosis through degradation of MYH9 and enhances sensitivity to paclitaxel in breast cancer

JX Song, Y Wang, ZP Hua, Y Huang, LF Hu… - Cell Death & …, 2024 - nature.com
Breast cancer is one of the most prevalent and diverse malignancies, and, with global cases
increasing, the need for biomarkers to inform individual sensitivity to chemotherapeutics has …

Management of adverse reactions induced by chemotherapy drugs

DB Abreu, JR Cernadas - Current Opinion in Allergy and Clinical …, 2022 - journals.lww.com
Management of adverse reactions induced by chemotherapy drug... : Current Opinion in
Allergy and Clinical Immunology Management of adverse reactions induced by chemotherapy …

Combination of H1 and H2 Histamine Receptor Antagonists: Current Knowledge and Perspectives of a Classic Treatment Strategy

E Kou, X Zhang, B Dong, B Wang, Y Zhu - Life, 2024 - mdpi.com
Histamine receptor antagonists, which can bind to specific histamine receptors on target
cells, exhibit substantial therapeutic efficacy in managing a variety of histamine-mediated …

Repurposing of H1-receptor antagonists (levo)cetirizine, (des)loratadine, and fexofenadine as a case study for systematic analysis of trials on clinicaltrials.gov using …

T Specht, R Seifert - Naunyn-schmiedeberg's Archives of Pharmacology, 2024 - Springer
To gain a comprehensive overview of the landscape of clinical trials for the H1-receptor
antagonists (H1R antagonists) cetirizine, levocetirizine, loratadine, desloratadine, and …

Hypersensitivity reaction and rapid drug desensitization with chemotherapeutics: a tertiary reference center experiences

İ Bulut, Z Yegin Katran - International Archives of Allergy and …, 2023 - karger.com
Introduction: Chemotherapy drugs have been in our lives for a long time, and all agents
have the potential to develop hypersensitivity. Rapid drug desensitization is an option when …

[HTML][HTML] Glucocorticoid Receptor Isoforms in Breast Cancer Raise Implications for Personalised Supportive Therapies

H Butz, V Vereczki, B Budai, G Rubovszky… - International Journal of …, 2024 - mdpi.com
Glucocorticoid receptor (GR) activation may promote metastasis in oestrogen receptor-
negative and triple-negative breast cancer (TNBC). However, the role of the GRβ isoform …

[HTML][HTML] C118P Suppresses Gastric Cancer Growth via Promoting Autophagy–Lysosomal Degradation of RAB1A

S Wei, J Zhang, H Wu, Z Liao, Z Liu, Y Hou… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background/Objectives: Gastric cancer (GC) is the leading cause of cancer-related deaths
worldwide. C118P, a microtubule inhibitor with anti-angiogenic and vascular-disrupting …

A three-step taxane titration protocol decreases hypersensitivity reactions during first and second exposures

DM Lynch, S Menon, E Mazzola, J Costa… - JCO Oncology …, 2023 - ascopubs.org
INTRODUCTION: Patients receiving taxanes are at risk for developing hypersensitivity
reactions (HSRs) primarily during first and second lifetime exposures. Immediate HSRs …