Altered hemodynamics and end-organ damage in heart failure: impact on the lung and kidney

FH Verbrugge, M Guazzi, JM Testani, BA Borlaug - Circulation, 2020 - Am Heart Assoc
Heart failure is characterized by pathologic hemodynamic derangements, including elevated
cardiac filling pressures (“backward” failure), which may or may not coexist with reduced …

Pulmonary Hypertension in HFpEF and HFrEF: JACC Review Topic of the Week

M Guazzi, S Ghio, Y Adir - Journal of the American College of Cardiology, 2020 - jacc.org
Pulmonary hypertension (PH) associated with left heart disease, or Group 2 PH, includes
heart failure, valvular heart diseases, and congenital heart diseases. Although it is axiomatic …

Exercise testing in heart failure with preserved ejection fraction: an appraisal through diagnosis, pathophysiology and therapy–A clinical consensus statement of the …

M Guazzi, M Wilhelm, M Halle… - European journal of …, 2022 - Wiley Online Library
Patients with heart failure with preserved ejection fraction (HFpEF) universally complain of
exercise intolerance and dyspnoea as key clinical correlates. Cardiac as well as …

Heart failure with preserved ejection fraction—a concise review

DM Adamczak, MT Oduah, T Kiebalo… - Current cardiology …, 2020 - Springer
Abstract Purpose of Review Heart failure with preserved ejection fraction (HFpEF) is a
relatively new disease entity used in medical terminology; however, both the number of …

The controversial role of beta-blockers in heart failure with preserved ejection fraction

S Wernhart, M Papathanasiou, T Rassaf… - Pharmacology & …, 2023 - Elsevier
Beta-blocker (BB) therapy is a main pillar in treating patients with heart failure and reduced
ejection fraction and has shown a prognostic benefit. However, evidence for application of …

Kernel parameter tuning to tweak the performance of classifiers for identification of heart diseases

A Dhankhar, S Juneja, A Juneja, V Bali - International Journal of E …, 2021 - igi-global.com
Medical data analysis is being recognized as a field of enormous research possibilities due
to the fact there is a huge amount of data available and prediction in initial stage may save …

Exercise-induced pulmonary hypertension in HFpEF and HFrEF: different pathophysiologic mechanism behind similar functional impairment

NR Pugliese, M Mazzola, R Madonna, L Gargani… - Vascular …, 2022 - Elsevier
Aims Pathophysiological mechanisms behind cardio-pulmonary impairment in heart failure
(HF) with reduced (HFrEF) and preserved (HFpEF) ejection fraction are likely different. We …

Sodium-glucose co-transporter 2 inhibitors in heart failure with mildly reduced or preserved ejection fraction: an updated systematic review and meta-analysis

Y Wang, T Gao, C Meng, S Li, L Bi, Y Geng… - European journal of …, 2022 - Springer
Objectives Heart failure with mildly reduced ejection fraction (HFmrEF) or heart failure with
preserved ejection fraction (HFpEF) are associated with significant morbidity and mortality …

Sodium glucose co-transporter 2 inhibitors in heart failure with preserved ejection fraction: a systematic review and meta-analysis

V Tsampasian, H Elghazaly… - European Journal of …, 2022 - academic.oup.com
Whilst heart failure with preserved ejection fraction (HFpEF) is increasingly studied, the
search for a single pharmacotherapeutic agent that will improve hard endpoints like …

Biatrial myopathy in heart failure with preserved ejection fraction

K Omote, H Sorimachi, M Obokata… - European Journal of …, 2024 - Wiley Online Library
Aim Left atrial (LA) myopathy is increasingly recognized as an important phenotypic trait in
heart failure (HF) with preserved ejection fraction (HFpEF). Right atrial (RA) remodelling and …