Microarrays with biomolecules (eg, DNA and proteins), cells, and tissues immobilized on
solid substrates are important tools for biological research, including genomics, proteomics …

The use of antibodies as recognition elements in bioanalytical assays can be traced back to
the late 1950s. Yalow and Berson (1) pioneered radioimmunoassay for measurement of …

The encapsulation of enzymes and other proteins into inorganic host materials has attracted
considerable attention over the past few years. This research has demonstrated that …

The direct patterning of biomolecules on a solid substrate can be achieved using
microcontact printing, a method that has been very successfully adopted for the precise and …

Infrared− visible sum frequency generation (SFG) vibrational spectroscopy, in combination
with fluorescence microscopy, was employed to investigate the surface structure of …

The adsorption of lysozyme on the mesoporous molecular sieves MCM-41 and SBA-15 from
buffered solutions with different pH values has been studied as a model protein adsorption …

Intact, multiply protonated proteins of particular mass and charge were selected from ionized
protein mixtures and gently landed at different positions on a surface to form a microarray …

We compare the catalytic activities of enzymes immobilized on silicon surfaces with and
without orientation. While oriented sulfotransferases selectively immobilized on an otherwise …

A fiber-optic biosensor using an aptamer receptor has been developed for the measurement
of thrombin. An antithrombin DNA aptamer was immobilized on the surface of silica …

We report an observation of a peculiar effect in which the vibrational frequencies of antibody-
conjugated SERS-active reporter molecules are shifted in quantitative correlation with the …