Neuroprotective effects of coffee bioactive compounds: a review

K Socała, A Szopa, A Serefko, E Poleszak… - International journal of …, 2020 - mdpi.com
Coffee is one of the most widely consumed beverages worldwide. It is usually identified as a
stimulant because of a high content of caffeine. However, caffeine is not the only coffee …

Neuroinflammation as a key driver of secondary neurodegeneration following stroke?

SM Stuckey, LK Ong, LE Collins-Praino… - International Journal of …, 2021 - mdpi.com
Ischaemic stroke involves the rapid onset of focal neurological dysfunction, most commonly
due to an arterial blockage in a specific region of the brain. Stroke is a leading cause of …

Noninvasive detection of cuprizone induced axonal damage and demyelination in the mouse corpus callosum

SW Sun, HF Liang, K Trinkaus… - … in Medicine: An …, 2006 - Wiley Online Library
Previously, we tested the prediction that axonal damage results in decreased axial diffusivity
(λ∥) while demyelination leads to increased radial diffusivity (λ⟂). Cuprizone treatment of …

Recent advancements of nanomedicine in neurodegenerative disorders theranostics

S Mukherjee, VS Madamsetty… - Advanced Functional …, 2020 - Wiley Online Library
Recent times have witnessed an upsurge in the incidence of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Prion disease, and …

Selective neuronal loss in ischemic stroke and cerebrovascular disease

JC Baron, H Yamauchi, M Fujioka… - Journal of Cerebral …, 2014 - journals.sagepub.com
As a sequel of brain ischemia, selective neuronal loss (SNL)—as opposed to pannecrosis
(ie infarction)—is attracting growing interest, particularly because it is now detectable in vivo …

Magnetic resonance imaging evidence for presymptomatic change in thalamus and caudate in familial Alzheimer's disease

NS Ryan, S Keihaninejad, TJ Shakespeare… - Brain, 2013 - academic.oup.com
Amyloid imaging studies of presymptomatic familial Alzheimer's disease have revealed the
striatum and thalamus to be the earliest sites of amyloid deposition. This study aimed to …

Secondary neurodegeneration in remote regions after focal cerebral infarction: a new target for stroke management?

J Zhang, Y Zhang, S Xing, Z Liang, J Zeng - Stroke, 2012 - Am Heart Assoc
Cerebral infarction-induced cessation of function in areas of the brain remote from, but
connected to, the primary site of damage was termed “diaschisis” by von Monakow. 1 …

Dynamic regional brain atrophy rates in the first year after ischemic stroke

A Brodtmann, MS Khlif, N Egorova, M Veldsman… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: Brain atrophy can be regarded as an end-organ effect of
cumulative cardiovascular risk factors. Accelerated brain atrophy is described following …

Acute infarcts cause focal thinning in remote cortex via degeneration of connecting fiber tracts

M Duering, R Righart, FA Wollenweber, V Zietemann… - Neurology, 2015 - AAN Enterprises
Objective: To study remote effects distant from acute ischemic infarcts by measuring
longitudinal changes of cortical thickness in connected brain regions as well as changes in …

Found in translation: preclinical stroke research predicts human pathophysiology, clinical phenotypes, and therapeutic outcomes

U Dirnagl, M Endres - Stroke, 2014 - Am Heart Assoc
Dirnagl and Endres Found in Translation 1511 has failed to deliver evidence for a clinical
benefit of any of the neuroprotectants tested. Recent examples include erythropoietin, 18 …