Diabetes and sarcopenic obesity: pathogenesis, diagnosis, and treatments

M Wang, Y Tan, Y Shi, X Wang, Z Liao… - Frontiers in …, 2020 - frontiersin.org
Sarcopenic obesity and diabetes are two increasing health problems worldwide, which both
share many common risk factors, such as aging, and general obesity. The pathogenesis of …

Diabetes and cancer: risk, challenges, management and outcomes

RK Shahid, S Ahmed, D Le, S Yadav - Cancers, 2021 - mdpi.com
Simple Summary Diabetes mellitus is a common disease in patients with cancer. It is a risk
factor for certain cancers such as pancreatic, liver, colon, breast, and endometrial cancer …

American Association of Clinical Endocrinology clinical practice guideline: developing a diabetes mellitus comprehensive care plan—2022 update

L Blonde, GE Umpierrez, SS Reddy, JB McGill… - Endocrine Practice, 2022 - Elsevier
Objective The objective of this clinical practice guideline is to provide updated and new
evidence-based recommendations for the comprehensive care of persons with diabetes …

PPAR-α modulators as current and potential cancer treatments

Y Tan, M Wang, K Yang, T Chi, Z Liao, P Wei - Frontiers in oncology, 2021 - frontiersin.org
Cancer is one of the leading causes of mortality worldwide. PPAR modulators may hold
great potential for the management of cancer patients. Indeed, PPARs are critical sensors …

mRNA vaccine in cancer therapy: Current advance and future outlook

Y Li, M Wang, X Peng, Y Yang, Q Chen… - Clinical and …, 2023 - Wiley Online Library
Messenger ribonucleic acid (mRNA) vaccines are a relatively new class of vaccines that
have shown great promise in the immunotherapy of a wide variety of infectious diseases and …

High glucose: an emerging association between diabetes mellitus and cancer progression

S Supabphol, W Seubwai, S Wongkham… - Journal of Molecular …, 2021 - Springer
The association of cancer and diabetes mellitus (DM) has been studied for decades.
Hyperglycemia and the imbalance of hormones are factors that contribute to the molecular …

Obesity and main urologic cancers: Current systematic evidence, novel biological mechanisms, perspectives and challenges

G Papavasileiou, D Tsilingiris, N Spyrou… - Seminars in Cancer …, 2023 - Elsevier
Urologic cancers (UC) account for 13.1% of all new cancer cases and 7.9% of all cancer-
related deaths. A growing body of evidence has indicated a potential causal link between …

Repurposing drugs targeting metabolic diseases for cancer therapeutics

J Pillai, A Ray, M Maan, M Dutta - Drug Discovery Today, 2023 - Elsevier
Highlights•Discovery of new drugs against cancer is of utmost importance.•Drug repurposing
is an alternative approach to traditional drug discovery.•It significantly reduces the R&D …

Non-coding RNA as biomarkers for type 2 diabetes development and clinical management

T Chi, J Lin, M Wang, Y Zhao, Z Liao… - Frontiers in …, 2021 - frontiersin.org
Diabetes, a metabolic disease characterized by high blood glucose and other complications,
has undefined causes and multiple risk factors, including inappropriate diet, unhealthy …

Endogenous stimuli-responsive nanoparticles for cancer therapy: from bench to bedside

F Xie, M Wang, Q Chen, T Chi, S Zhu, P Wei… - Pharmacological …, 2022 - Elsevier
Cancer is complicated to treat because of its high propensity for recurrence and metastasis,
and various side effects of conventional cancer treatments. With the development of …