Frailty and delirium are two common geriatric syndromes sharing several clinical
characteristics, risk factors, and negative outcomes. Understanding their interdependency is …

Many factors have contributed to rendering frailty an emerging, relevant, and very popular
concept. First, many pandemics that have affected humanity in history, including COVID-19 …

Background Dementia and frailty are common age-related syndromes often linked to chronic
inflammation. Identifying the biological factors and pathways that contribute to chronic …

Introduction Frailty is a geriatric syndrome that is highly susceptible to adverse health
outcomes and is a major burden that exacerbates society's medical care. By investigating …

Frailty in older adults is associated with greater risk of cognitive decline. Brain connectivity
insights could help understand the association, but studies are lacking. We applied …

The ageing of an organism is associated with certain features of functional decline that can
be assessed at the cellular level (eg, reduced telomere length, loss of proteostasis, etc.), but …

Background: Altered cell homeostasis, seen in cognitive decline and frailty, leads to cell
death and turnover, releasing circulating cell-free DNA (ccf-DNA). Objective: The goal of this …

Background Cognitive impairment and physical frailty are common among older adults and
associated with a higher likelihood of adverse health outcomes. These two conditions …

Background Loneliness is highly prevalent among older adults and is associated with frailty.
Most studies consider loneliness in isolation without consideration for structural and …

Background This study aimed to assess the associations of orthostatic hypotension (OH), in
the presence or absence of frailty, with dementia and mortality in older adults. Methods We …