The highly evolutionarily conserved serotonin transporter (SERT) regulates the entire
serotoninergic system and its receptors via mod-ulation of extracellular fluid serotonin …

A thorough investigation of the neural effects of psychotherapy is needed in order to provide
a neurobiological foundation for widely used treatment protocols. This paper reviews …

Background Depression is associated with interpersonal difficulties related to abnormalities
in affective facial processing. Objectives To map brain systems activated by sad facial affect …

OBJECTIVE: Minimum therapeutic doses of paroxetine and citalopram produce 80%
occupancy for the serotonin (5-HT) transporter (5-HTT). The authors used [11C] DASB …

Context The need for improved therapeutic agents that more quickly and effectively treat
depression is critical. In a pilot study we evaluated the role of the cholinergic system in …

Interest in serotonergic involvement in Parkinson's disease (PD) has focussed recently on
the possibility that the remaining serotonin neurons innervating striatum (caudate and …

Given the array of biological changes induced by stressors, it is not surprising that these
experiences may provoke a variety of illnesses. Among others things, stressors promote …

Serotonin is one of the most important neurotransmitters influencing mental health and, thus,
is a potential target for pharmaco-logical treatments. Functional neuroimaging techniques …

Definitive conclusions on the role of serotonin receptors and transporter in suicide and
depression have been elusive in studies of postmortem brain tissue. A number of …

Depression is a leading cause of morbidity and mortality, and its treatment includes a high
percentage of the medications prescribed by physicians. Available antidepressant drugs are …