Differential Effect of Non-Steroidal Anti-Inflammatory Drugs Aspirin and Naproxen against TMPRSS2-ERG (Fusion)-Driven and Non-Fusion-Driven Prostate Cancer

K Raina, K Kandhari, R Kant, RR Prasad, N Mishra… - Cancers, 2023 - mdpi.com
Simple Summary Disparity in clinical outcome data due to the biological heterogeneity of
prostate cancer (PCa) has drawn attention to approaches that stratify homogeneous subsets …

The role of protein post-translational modifications in prostate cancer

Y Hao, C Gu, W Luo, J Shen, F Xie, Y Zhao, X Song… - PeerJ, 2024 - peerj.com
Involving addition of chemical groups or protein units to specific residues of the target
protein, post-translational modifications (PTMs) alter the charge, hydrophobicity, and …

[HTML][HTML] From microscopes to molecules: The evolution of prostate cancer diagnostics

J Tao, X Bian, J Zhou, M Zhang - CytoJournal, 2024 - pmc.ncbi.nlm.nih.gov
In the ever-evolving landscape of oncology, the battle against prostate cancer (PCa) stands
at a transformative juncture, propelled by the integration of molecular diagnostics into …

Stage-specific effect of inositol hexaphosphate on cancer stem cell pool during growth and progression of prostate tumorigenesis in TRAMP model

K Raina, K Kandhari, AK Jain, K Ravichandran… - Cancers, 2022 - mdpi.com
Simple Summary The stage of a tumor during cancer intervention is the most crucial factor
that determines the treatment regimen. Several bioactive natural compounds have shown …

PLA inhibits TNF-α-induced PANoptosis of prostate cancer cells through metabolic reprogramming

Y Hao, F Xie, J He, C Gu, Y Zhao, W Luo… - … International Journal of …, 2024 - Elsevier
Previous studies have shown that phenyllactic acid (alpha-Hydroxyhydrocinnamic acid, 2-
Hydroxy-3-phenylpropionic acid, PLA), a type of organic acid metabolite, has excellent …

Effect of nonsteroidal anti‐inflammatory drugs (aspirin and naproxen) on inflammation‐associated proteomic profiles in mouse plasma and prostate during TMPRSS2 …

RR Prasad, N Mishra, R Kant, JT Fox… - Molecular …, 2024 - Wiley Online Library
Recent preclinical studies have shown that the intake of nonsteroidal anti‐inflammatory
drugs (NSAIDs) aspirin and naproxen could be an effective intervention strategy against …