The role of microenvironment in tumor angiogenesis

X Jiang, J Wang, X Deng, F Xiong, S Zhang… - Journal of Experimental …, 2020 - Springer
Tumor angiogenesis is necessary for the continued survival and development of tumor cells,
and plays an important role in their growth, invasion, and metastasis. The tumor …

Pustular psoriasis: from pathophysiology to treatment

G Genovese, C Moltrasio, N Cassano, CA Maronese… - Biomedicines, 2021 - mdpi.com
Pustular psoriasis (PP) is a clinicopathological entity encompassing different variants, ie,
acute generalized PP (GPP), PP of pregnancy (impetigo herpetiformis), annular (and …

Expression of SARS-CoV-2 receptor ACE2 and coincident host response signature varies by asthma inflammatory phenotype

M Camiolo, M Gauthier, N Kaminski, A Ray… - Journal of Allergy and …, 2020 - Elsevier
Background More than 300 million people carry a diagnosis of asthma, with data to suggest
that they are at a higher risk for infection or adverse outcomes from severe acute respiratory …

[HTML][HTML] Genome-wide association study on milk production and somatic cell score for Thai dairy cattle using weighted single-step approach with random regression …

S Buaban, K Lengnudum, W Boonkum… - Journal of Dairy …, 2022 - Elsevier
ABSTRACTS Genome-wide association studies are a powerful tool to identify genomic
regions and variants associated with phenotypes. However, only limited mutual confirmation …

Cytokine storm and mucus hypersecretion in COVID-19: review of mechanisms

MA Khan, ZA Khan, M Charles, P Pratap… - Journal of …, 2021 - Taylor & Francis
Mucus is an integral part of the respiratory physiology. It protects the respiratory tract by
acting as a physical barrier against inhaled particles and microbes. Excessive inflammation …

The Interleukin‐1 (IL‐1) superfamily cytokines and their single nucleotide polymorphisms (SNPs)

P Behzadi, AS Sameer, S Nissar… - Journal of …, 2022 - Wiley Online Library
Interleukins (ILs)—which are important members of cytokines—consist of a vast group of
molecules, including a wide range of immune mediators that contribute to the immunological …

[HTML][HTML] Proprotein convertase subtilisin/kexin type 9 is a psoriasis-susceptibility locus that is negatively related to IL36G

A Merleev, A Ji-Xu, A Toussi, LC Tsoi, ST Le… - JCI insight, 2022 - ncbi.nlm.nih.gov
Proprotein convertase subtilisin/kexin type-9 (PCSK9) is a posttranslational regulator of the
LDL receptor (LDLR). Recent studies have proposed a role for PCSK9 in regulating immune …

Interleukin-1 in Coronary Artery Disease

E Oikonomou, P Tsaplaris, A Anastasiou… - Current Topics in …, 2022 - ingentaconnect.com
Cardiovascular disease is the leading cause of mortality worldwide. Inflammation has long
been established as a key component in the pathophysiology of coronary artery disease …

Inhibition of A1 astrocytes and activation of A2 astrocytes for the treatment of spinal cord injury

J Wang, C Cheng, Z Liu, Y Lin, L Yang, Z Zhang… - Neurochemical …, 2023 - Springer
Spinal cord injury (SCI) is a serious injury to the central nervous system that causes
significant physical and psychological trauma to the patient. SCI includes primary spinal …

Cytokine pathways and investigational target therapies in hidradenitis suppurativa

E Del Duca, P Morelli, L Bennardo… - International journal of …, 2020 - mdpi.com
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease affecting
areas with a high density of apocrine glands and characterized by subcutaneous nodules …