Glutamatergic neurotransmission: A potential pharmacotherapeutic target for the treatment of cognitive disorders
P Chakraborty, A Dey, AV Gopalakrishnan… - Ageing Research …, 2023 - Elsevier
In the mammalian brain, glutamate is regarded to be the primary excitatory neurotransmitter
due to its widespread distribution and wide range of metabolic functions. Glutamate plays …
due to its widespread distribution and wide range of metabolic functions. Glutamate plays …
Progress in the development of kynurenine and quinoline-3-carboxamide-derived drugs
Introduction The diverse neuro-and immunomodulatory effects of kynurenine pathway (KP)
enzymes and metabolites exert offer possibilities for intervention in diseases such as …
enzymes and metabolites exert offer possibilities for intervention in diseases such as …
Biosynthesis of l‐4‐Chlorokynurenine, an Antidepressant Prodrug and a Non‐Proteinogenic Amino Acid Found in Lipopeptide Antibiotics
Abstract l‐4‐Chlorokynurenine (l‐4‐Cl‐Kyn) is a neuropharmaceutical drug candidate that is
in development for the treatment of major depressive disorder. Recently, this amino acid was …
in development for the treatment of major depressive disorder. Recently, this amino acid was …
A Novel Peptide Antibiotic Produced by Streptomyces roseoflavus Strain INA-Ac-5812 With Directed Activity Against Gram-Positive Bacteria
AS Vasilchenko, WT Julian, OA Lapchinskaya… - Frontiers in …, 2020 - frontiersin.org
In this work, we report the isolation and detailed functional characterization for the new non-
ribosomally synthesized antibiotic 5812-A/C, which was derived from metabolites of …
ribosomally synthesized antibiotic 5812-A/C, which was derived from metabolites of …
Gausemycins A,B: Cyclic Lipoglycopeptides from Streptomyces sp.**
AP Tyurin, VA Alferova, AS Paramonov… - Angewandte Chemie …, 2021 - Wiley Online Library
We report a novel family of natural lipoglycopeptides produced by Streptomyces sp. INA‐Ac‐
5812. Two major components of the mixture, named gausemycins A and B, were isolated …
5812. Two major components of the mixture, named gausemycins A and B, were isolated …
Structure-activity studies of irumamycin type macrolides from Streptomyces sp. INA-Ac-5812
VA Alferova, MV Shuvalov, RA Novikov, AS Trenin… - Tetrahedron …, 2019 - Elsevier
Three natural glycosylated macrolide compounds, known irumamycin 1 and X-14952B 2, as
well as new isoirumamycin 3, were isolated from ethyl acetate mycelium extract of …
well as new isoirumamycin 3, were isolated from ethyl acetate mycelium extract of …
[PDF][PDF] Біосинтез розеофунгіну Streptomyces roseoflavus subsp. roseofungini
КВ Кравець - 2024 - dspace.nuft.edu.ua
РЕФЕРАТ Метою даної кваліфікаційної роботи є розробка апаратурної та технологічної
схеми біосинтезу вторинного метаболіту фунгіциду розеофунгіну з використанням …
схеми біосинтезу вторинного метаболіту фунгіциду розеофунгіну з використанням …
[HTML][HTML] Nampt Receptor
Introduction: The diverse neuro-and immunomodulatory effects of kynurenine pathway (KP)
enzymes and metabolites exert offer possibilities for intervention in diseases such as …
enzymes and metabolites exert offer possibilities for intervention in diseases such as …
[HTML][HTML] Biosynthesis of L-4-Chlorokynurenine, a Lipopeptide Antibiotic Non-Proteinogenic Amino Acid and Antidepressant Prodrug
Abstract L-4-Chlorokynurenine (L-4-Cl-Kyn) is a neuropharmaceutical drug candidate in
development for the treatment of major depressive disorder. Recently, this amino acid was …
development for the treatment of major depressive disorder. Recently, this amino acid was …
4-L-ХЛОРКИНУРЕНИН КАК ФЛУОРЕСЦЕНТНАЯ АМИНОКИСЛОТА В ПРИРОДНЫХ ПЕПТИДАХ
ВА Алферова, АП Тюрин, МВ Шувалов… - … химии, фармацевтики и …, 2019 - elibrary.ru
При изучении штамма Streptomyces sp. INA Ac 5812 было обнаружено, что
антибактериальная активность этого штамма связана со сложным антибиотическим …
антибактериальная активность этого штамма связана со сложным антибиотическим …