Acute myocardial infarction (AMI) and the heart failure that often follows, are major causes of
death and disability worldwide. As such, new therapies are required to limit myocardial …

The heart contains a population of resident macrophages that markedly expands following
injury through recruitment of monocytes and through proliferation of macrophages. In …

In the infarcted myocardium, cardiomyocyte necrosis triggers an intense inflammatory
reaction that not only is critical for cardiac repair, but also contributes to adverse remodeling …

Chemokine is a structure-related protein with a relatively small molecular weight, which can
target cells to chemotaxis and promote inflammatory response. Inflammation plays an …

Following acute occlusion of a coronary artery causing myocardial ischemia and
implementing first-line treatment involving rapid reperfusion, a dynamic and balanced …

Reperfusion therapy is widely used to treat acute myocardial infarction. However, its efficacy
is limited by myocardial ischemia-reperfusion injury (MIRI), which occurs paradoxically due …

The adult mammalian heart has limited endogenous regenerative capacity and heals
through the activation of inflammatory and fibrogenic cascades that ultimately result in the …

Phagocytosis after myocardial infarction (MI) is a prerequisite to cardiac repair. Recruited
monocytes clear necrotic cardiomyocytes and differentiate into cardiac macrophages. Some …

Purpose. Oxaliplatin is a platinum‐based chemotherapeutic agent demonstrating significant
antitumor efficacy. Unlike conventional anticancer agents which are immunosuppressive …

Background Inflammation has been implicated in the pathogenesis of coronary heart
disease, but the relevance and independence of individual inflammatory proteins is …