Kinetochores are large protein assemblies that connect chromosomes to microtubules of the
mitotic and meiotic spindles in order to distribute the replicated genome from a mother cell to …

The centromere is the region of the chromosome that directs its segregation in mitosis and
meiosis. Although the functional importance of the centromere has been appreciated for …

Inheritance of genomic DNA underlies the vast majority of biological inheritance, yet it has
been clear for decades that additional epigenetic information can be passed on to future …

The function of sperm is to safely transport the haploid paternal genome to the egg
containing the maternal genome. The subsequent fertilization leads to transmission of a new …

The production of haploids is an important first step in creating many new plant varieties.
One approach used in Arabidopsis involves crossing plants expressing different forms of …

Wide crosses result in postzygotic elimination of one parental chromosome set, but the
mechanisms that result in such differential fate are poorly understood. Here, we show that …

Female meiosis provides an opportunity for selfish genetic elements to violate Mendel's law
of segregation by increasing the chance of segregating to the egg [1]. Centromeres and …

The centromere, responsible for chromosome segregation during mitosis, is epigenetically
defined by CENP-A containing chromatin. The amount of centromeric CENP-A has direct …

Wolbachia are widespread endosymbiotic bacteria that manipulate the reproduction of
arthropods through a diversity of cellular mechanisms. In cytoplasmic incompatibility (CI), a …

The ability to generate (doubled) haploid plants significantly accelerates the crop breeding
process. Haploids have been induced mainly through the generation of plants from …