Mitochondrial DNA copy number and risk of diabetes mellitus and metabolic syndrome

C Huang, L Chen, J Li, J Ma, J Luo, Q Lv… - The Journal of …, 2024 - academic.oup.com
Abstract Context Mitochondrial DNA (mtDNA) plays a key role in diabetes mellitus and
metabolic syndrome (MetS). An increasing number of studies have reported the association …

Mitochondrial DNA copy number: linking diabetes and cancer

AA Memon, S Vats, J Sundquist, Y Li… - Antioxidants & Redox …, 2022 - liebertpub.com
Recent Advances: Various studies have suggested that mitochondrial DNA copy number
(mtDNA-CN), a surrogate biomarker of mitochondrial dysfunction, is an easily quantifiable …

D-loop mutations in mitochondrial DNA are a risk factor for chemotherapy resistance in esophageal cancer

T Harino, K Tanaka, D Motooka, Y Masuike… - Scientific Reports, 2024 - nature.com
Esophageal cancer is a highly aggressive disease, and acquired resistance to
chemotherapy remains a significant hurdle in its treatment. mtDNA, crucial for cellular …

[HTML][HTML] Mitochondrial DNA copy number in adults with and without Type 1 diabetes

AJ Jenkins, LM Carroll, MLH Huang, Y Wen-Loh… - Diabetes Research and …, 2023 - Elsevier
Aims Mitochondrial damage is implicated in diabetes pathogenesis and complications.
Mitochondrial DNA copy number (mtDNA-cn) in human Type 1 diabetes (T1D) studies are …

Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs

M Dashti, NM Ali, H Alsaleh, SE John… - Frontiers in …, 2024 - frontiersin.org
Background Numerous studies have linked mitochondrial dysfunction to the development of
type 2 diabetes (T2D) by affecting glucose-stimulated insulin secretion in pancreatic beta …

Nuclear and mitochondrial DNA alterations in pheochromocytomas and paragangliomas, and their potential treatment

M Tabebi, P Söderkvist, O Gimm - Endocrine-Related Cancer, 2023 - erc.bioscientifica.com
Mitochondrial DNA (mtDNA) alterations have been reported in different types of cancers and
are suggested to play important roles in cancer development and metastasis. However …

Characterization of mitochondrial DNA mutations in colorectal cancer progression by in silico approach and use as potential biomarkers for diagnosis and prognosis

R Gadicherla, N Rai, R Othayoth, S Kamma - Egyptian Journal of Medical …, 2024 - Springer
Mitochondrial DNA variants are significant contributors to cancer progression, as evidenced
by numerous findings. This study focuses on characterizing mitochondrial DNA mutations in …

Serum oxidative stressors levels and association of mtDNA variants with type 2 diabetes mellitus in the Central India population

T Tajane, P Ambulkar, P Waghmare, B Taksande… - Human Gene, 2024 - Elsevier
Background The mitochondrial genome has a high rate of mutability which plays a major
role in pathogenic mutations. These mutations are implicated with mitochondrial dysfunction …

[PDF][PDF] 2 型糖尿病相关的线粒体基因突变研究系统回顾

林婷, 周乐, 陈涛 - 大连医科大学学报, 2023 - journal.dmu.edu.cn
线粒体通过氧化磷酸化以三磷酸腺苷的形式为细胞代谢提供能量. 线粒体DNA (mitochondria
DNA, mtDNA) 突变会导致多种疾病的发生, 包括线粒体脑肌病, Leber 遗传性视神经病 …

Identification, genetic diversity, and comparative evolution of the striped snakehead Channa striata (Bloch, 1793) in Wallacea, Indonesia

I IRMAWATI, M MEIMULYA… - Biodiversitas Journal of …, 2022 - smujo.id
Irmawati, Meimulya, Tassakka ACMAR, Nadiarti, Rukminasari N, Kadriah IAK, Nasrullah H,
Alimuddin. 2022. Identification, genetic diversity, and comparative evolution of the striped …