AA Memon, S Vats, J Sundquist, Y Li… - Antioxidants & Redox …, 2022 - liebertpub.com
Recent Advances: Various studies have suggested that mitochondrial DNA copy number (mtDNA-CN), a surrogate biomarker of mitochondrial dysfunction, is an easily quantifiable …
T Harino, K Tanaka, D Motooka, Y Masuike… - Scientific Reports, 2024 - nature.com
Esophageal cancer is a highly aggressive disease, and acquired resistance to chemotherapy remains a significant hurdle in its treatment. mtDNA, crucial for cellular …
AJ Jenkins, LM Carroll, MLH Huang, Y Wen-Loh… - Diabetes Research and …, 2023 - Elsevier
Aims Mitochondrial damage is implicated in diabetes pathogenesis and complications. Mitochondrial DNA copy number (mtDNA-cn) in human Type 1 diabetes (T1D) studies are …
M Dashti, NM Ali, H Alsaleh, SE John… - Frontiers in …, 2024 - frontiersin.org
Background Numerous studies have linked mitochondrial dysfunction to the development of type 2 diabetes (T2D) by affecting glucose-stimulated insulin secretion in pancreatic beta …
M Tabebi, P Söderkvist, O Gimm - Endocrine-Related Cancer, 2023 - erc.bioscientifica.com
Mitochondrial DNA (mtDNA) alterations have been reported in different types of cancers and are suggested to play important roles in cancer development and metastasis. However …
R Gadicherla, N Rai, R Othayoth, S Kamma - Egyptian Journal of Medical …, 2024 - Springer
Mitochondrial DNA variants are significant contributors to cancer progression, as evidenced by numerous findings. This study focuses on characterizing mitochondrial DNA mutations in …
Background The mitochondrial genome has a high rate of mutability which plays a major role in pathogenic mutations. These mutations are implicated with mitochondrial dysfunction …