[HTML][HTML] Protective non-neutralizing SARS-CoV-2 monoclonal antibodies

A Izadi, P Nordenfelt - Trends in immunology, 2024 - cell.com
Recent studies show an important role for non-neutralizing anti-spike antibodies, including
monoclonal antibodies (mAbs), in robustly protecting against SARS-CoV-2 infection. These …

B-cell and antibody responses to SARS-CoV-2: infection, vaccination, and hybrid immunity

D Lapuente, TH Winkler, M Tenbusch - Cellular & Molecular …, 2024 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019
prompted scientific, medical, and biotech communities to investigate infection-and vaccine …

Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus

J Lee, SK Zepeda, YJ Park, AL Taylor, J Quispe… - Cell Host & Microbe, 2023 - cell.com
Although Rhinolophus bats harbor diverse clade 3 sarbecoviruses, the structural
determinants of receptor tropism along with the antigenicity of their spike (S) glycoproteins …

Mucosal vaccine-induced cross-reactive CD8+ T cells protect against SARS-CoV-2 XBB.1.5 respiratory tract infection

B Ying, TL Darling, P Desai, CY Liang, IP Dmitriev… - Nature …, 2024 - nature.com
A nasally delivered chimpanzee adenoviral-vectored severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) vaccine (ChAd-SARS-CoV-2-S) is currently used in India …

Mucosal adenovirus vaccine boosting elicits IgA and durably prevents XBB. 1.16 infection in nonhuman primates

M Gagne, BJ Flynn, SF Andrew, J Marquez… - Nature …, 2024 - nature.com
A mucosal route of vaccination could prevent severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) replication at the site of infection and limit transmission. We …

Progressive loss of conserved spike protein neutralizing antibody sites in Omicron sublineages is balanced by preserved T cell immunity

A Muik, BG Lui, J Quandt, H Diao, Y Fu, M Bacher… - Cell Reports, 2023 - cell.com
Evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron
variant has led to the emergence of sublineages with different patterns of neutralizing …

Randomized controlled trial reveals no benefit to a 3-month delay in COVID-19 mRNA booster vaccine

WS Lee, J Audsley, MC Trieu, A Reynaldi… - The Journal of Clinical …, 2024 - jci.org
BACKGROUND There is uncertainty about the timing of booster vaccination against COVID-
19 in highly vaccinated populations during the present endemic phase of COVID-19. Studies …

High-resolution map of the Fc functions mediated by COVID-19-neutralizing antibodies

I Paciello, G Maccari, E Pantano… - Proceedings of the …, 2024 - National Acad Sciences
A growing body of evidence shows that fragment crystallizable (Fc)-dependent antibody
effector functions play an important role in protection from severe acute respiratory …

[HTML][HTML] Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV

CW Chao, KR Sprouse, MC Miranda, NJ Catanzaro… - Cell Reports, 2024 - cell.com
Middle East respiratory syndrome coronavirus (MERS-CoV) is a betacoronavirus that
causes severe respiratory illness in humans. There are no licensed vaccines against MERS …

Vaccine development against tuberculosis before and after Covid-19

SHE Kaufmann - Frontiers in Immunology, 2023 - frontiersin.org
Coronavirus disease (Covid-19) has not only shaped awareness of the impact of infectious
diseases on global health. It has also provided instructive lessons for better prevention …